BRCA1-Ku80 Protein Interaction Enhances End-joining Fidelity of Chromosomal Double-strand Breaks in the G1Phase of the Cell Cycle

DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks

(2012) Tibor Pankotai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1

(2011) Lisa Dohrn et al.   BIOCHEMICAL JOURNAL

γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization

(2011) Markus Löbrich et al.   CELL CYCLE

BRCA1 requirement for the fidelity of plasmid DNA double-strand break repair in cultured breast epithelial cells

(2011) Eric G. Thompson et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Functional characterization connects individual patient mutations in ataxia telangiectasia mutated (ATM) with dysfunction of specific DNA double-strand break-repair signaling pathways

(2011) Marlen Keimling et al.   FASEB JOURNAL

Human Ku70/80 Protein Blocks Exonuclease 1-mediated DNA Resection in the Presence of Human Mre11 or Mre11/Rad50 Protein Complex

(2011) Jingxin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

Release of Ku and MRN from DNA Ends by Mre11 Nuclease Activity and Ctp1 Is Required for Homologous Recombination Repair of Double-Strand Breaks

(2011) Petra Langerak et al.   PLoS Genetics

Identification of Breast Tumor Mutations in BRCA1 That Abolish Its Function in Homologous DNA Recombination

(2010) D. J.R. Ransburgh et al.   CANCER RESEARCH

Comprehensive Analysis of Missense Variations in the BRCT Domain of BRCA1 by Structural and Functional Assays

(2010) Megan S. Lee et al.   CANCER RESEARCH

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4–ligase IV during chromosomal translocation formation

(2010) Deniz Simsek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1

(2010) Verena Quennet et al.   NUCLEIC ACIDS RESEARCH

Xrcc1-dependent and Ku-dependent DNA double-strand break repair kinetics in Arabidopsis plants

(2010) Cyril Charbonnel et al.   PLANT JOURNAL

Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

(2010) S. Fnu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

Exonuclease Function of Human Mre11 Promotes Deletional Nonhomologous End Joining

(2009) Jing Zhuang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK–dependent repair in mice

(2009) Eddy S. Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of RNA Polymerase III Transcription by BRCA1

(2009) Ingrid Veras et al.   JOURNAL OF MOLECULAR BIOLOGY

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle

(2009) Maximina H. Yun et al.   NATURE

Multiple functions of MRN in end-joining pathways during isotype class switching

(2009) Maria Dinkelmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

(2009) Anyong Xie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

(2009) Emilie Rass et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Limiting the Persistence of a Chromosome Break Diminishes Its Mutagenic Potential

(2009) Nicole Bennardo et al.   PLoS Genetics

A sensitive test for the detection of specific DSB repair defects in primary cells from breast cancer specimens

(2008) Marlen Keimling et al.   INTERNATIONAL JOURNAL OF CANCER

Cell Cycle-dependent Complex Formation of BRCA1·CtIP·MRN Is Important for DNA Double-strand Break Repair

(2008) Longchuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid Recruitment of BRCA1 to DNA Double-Strand Breaks Is Dependent on Its Association with Ku80

(2008) L. Wei et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks

(2008) Leonie Schulte-Uentrop et al.   NUCLEIC ACIDS RESEARCH

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH

Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction

(2008) Craig B. Bennett et al.   PLoS One

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics