Ebsulfur Is a Benzisothiazolone Cytocidal Inhibitor Targeting the Trypanothione Reductase ofTrypanosoma brucei
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ebsulfur Is a Benzisothiazolone Cytocidal Inhibitor Targeting the Trypanothione Reductase ofTrypanosoma brucei
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 288, Issue 38, Pages 27456-27468
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2013-07-31
DOI
10.1074/jbc.m113.495101
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inhibition of thioredoxin reductase by a novel series of bis-1,2-benzisoselenazol-3(2H)-ones: Organoselenium compounds for cancer therapy
- (2012) Jie He et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Targeting Trypanothione Metabolism in Trypanosomatid Human Parasites
- (2012) Viridiana Olin-Sandoval et al. CURRENT DRUG TARGETS
- Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione
- (2012) Jun Lu et al. FASEB JOURNAL
- Bacillus anthracisThioredoxin Systems, Characterization and Role as Electron Donors for Ribonucleotide Reductase
- (2012) Tomas N. Gustafsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An efficient copper mediated synthetic methodology for benzo[d]isothiazol-3(2H)-ones and related sulfur–nitrogen heterocycles
- (2012) Bhagat Singh Bhakuni et al. TETRAHEDRON LETTERS
- Low-Molecular-Mass Antioxidants in Parasites
- (2011) R. Luise Krauth-Siegel et al. ANTIOXIDANTS & REDOX SIGNALING
- Antiparasitic prodrug nifurtimox: revisiting its activation mechanism
- (2011) Hugo Cerecetto et al. Future Microbiology
- Potent, Selective, and Orally Available Benzoisothiazolone Phosphomannose Isomerase Inhibitors as Probes for Congenital Disorder of Glycosylation Ia
- (2011) Russell Dahl et al. JOURNAL OF MEDICINAL CHEMISTRY
- Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography
- (2011) Stephen Patterson et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Dithiol Glutaredoxins of African Trypanosomes Have Distinct Roles and Are Closely Linked to the Unique Trypanothione Metabolism
- (2010) Sevgi Ceylan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity
- (2010) Elizabeth R. Sharlow et al. PLoS Neglected Tropical Diseases
- Investigation of Trypanothione Reductase as a Drug Target inTrypanosoma brucei
- (2009) Daniel Spinks et al. ChemMedChem
- Improved Tricyclic Inhibitors of Trypanothione Reductase by Screening and Chemical Synthesis
- (2009) John L. Richardson et al. ChemMedChem
- Comparative structural, kinetic and inhibitor studies of Trypanosoma brucei trypanothione reductase with T. cruzi
- (2009) Deuan C. Jones et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism
- (2008) R. Luise Krauth-Siegel et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More