Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality

How insulin engages its primary binding site on the insulin receptor

(2013) John G. Menting et al.   NATURE

Insulin and Insulin-like Growth Factor II Differentially Regulate Endocytic Sorting and Stability of Insulin Receptor Isoform A

(2012) Alaide Morcavallo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface

(2011) Emília Antolíková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adventures with Insulin in the Islets of Langerhans

(2011) Donald F. Steiner   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering of Insulin Receptor Isoform-Selective Insulin Analogues

(2011) Tine Glendorf et al.   PLoS One

Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues

(2010) J. Jiracek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The solution structure of a superpotent b-chain-shortened single-replacement insulin analogue

(2010) Günther Kurapkat et al.   PROTEIN SCIENCE

Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor

(2009) Colin W. Ward et al.   BIOESSAYS

Enhancing the Activity of a Protein by Stereospecific Unfolding

(2009) Qing-xin Hua et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning

(2009) Bin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Analogues with Modifications at Position B26. Divergence of Binding Affinity and Biological Activity†

(2008) Lenka Žáková et al.   BIOCHEMISTRY