Structures ofMycobacterium tuberculosisFadD10 Protein Reveal a New Type of Adenylate-forming Enzyme

Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein Domains

(2012) Carter A. Mitchell et al.   BIOCHEMISTRY

Adenylating Enzymes in Mycobacterium tuberculosis as Drug Targets

(2012) Benjamin P. Duckworth et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases

(2012) A. Chhabra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mycobacterium tuberculosis Very-Long-Chain Fatty Acyl-CoA Synthetase: Structural Basis for Housing Lipid Substrates Longer than the Enzyme

(2012) Charlotta S. Andersson et al.   STRUCTURE

Molecular Basis of the Functional Divergence of Fatty Acyl-AMP Ligase Biosynthetic Enzymes of Mycobacterium tuberculosis

(2011) Aneesh Goyal et al.   JOURNAL OF MOLECULAR BIOLOGY

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

Fatty acyl-AMP ligases and polyketide synthases are unique enzymes of lipid biosynthetic machinery in Mycobacterium tuberculosis

(2011) Debasisa Mohanty et al.   TUBERCULOSIS

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis

(2010) Roxane Siméone et al.   FEBS Journal

Attenuation ofMycobacterium tuberculosisFunctionally Disrupted in a Fatty Acyl–Coenzyme A Synthetase GenefadD5

(2010) Kathleen Y. Dunphy et al.   JOURNAL OF INFECTIOUS DISEASES

Structural and Functional Studies of Fatty Acyl Adenylate Ligases from E. coli and L. pneumophila

(2010) Zhening Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase

(2009) Andrew M. Gulick   ACS Chemical Biology

The Dual Function of the Mycobacterium tuberculosis FadD32 Required for Mycolic Acid Biosynthesis

(2009) Mathieu Léger et al.   CHEMISTRY & BIOLOGY

Adenylate-forming enzymes

(2009) Stefan Schmelz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Pks13/FadD32 Crosstalk for the Biosynthesis of Mycolic Acids inMycobacterium tuberculosis

(2009) Sabine Gavalda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Snapshots for the Conformation-dependent Catalysis by Human Medium-chain Acyl-coenzyme A Synthetase ACSM2A

(2009) Grazyna Kochan et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis

(2009) Pooja Arora et al.   Nature Chemical Biology

The 2.1 Å crystal structure of an acyl-CoA synthetase fromMethanosarcina acetivoransreveals an alternate acyl-binding pocket for small branched acyl substrates

(2009) Manish B. Shah et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Discovery of Amide (Peptide) Bond Synthetic Activity in Acyl-CoA Synthetase

(2008) Tomoko Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of DltA

(2008) Huma Yonus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY