Planar Cell Polarity Pathway Regulates Nephrin Endocytosis in Developing Podocytes

The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2

(2013) S. J. Warrington et al.   DEVELOPMENT

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity

(2012) S. Saburi et al.   DEVELOPMENT

VANGL2 regulates membrane trafficking of MMP14 to control cell polarity and migration

(2012) B. B. Williams et al.   JOURNAL OF CELL SCIENCE

Role of dynamin, synaptojanin, and endophilin in podocyte foot processes

(2012) Keita Soda et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes

(2012) Edwige Belotti et al.   PLoS One

Cell Biology and Pathology of Podocytes

(2011) Anna Greka et al.   Annual Review of Physiology

Principles of planar polarity in animal development

(2011) L. V. Goodrich et al.   DEVELOPMENT

Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney

(2011) X. Ye et al.   DEVELOPMENT

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

(2011) Y. Mao et al.   DEVELOPMENT

Dynamics of Core Planar Polarity Protein Turnover and Stable Assembly into Discrete Membrane Subdomains

(2011) Helen Strutt et al.   DEVELOPMENTAL CELL

Vangl2 Promotes Wnt/Planar Cell Polarity-like Signaling by Antagonizing Dvl1-Mediated Feedback Inhibition in Growth Cone Guidance

(2011) Beth Shafer et al.   DEVELOPMENTAL CELL

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

Wnt/β-Catenin Pathway in Podocytes Integrates Cell Adhesion, Differentiation, and Survival

(2011) Hideki Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKCα Mediates β-Arrestin2-dependent Nephrin Endocytosis in Hyperglycemia

(2011) Ivo Quack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt4 Enhances Murine Hematopoietic Progenitor Cell Expansion Through a Planar Cell Polarity-Like Pathway

(2011) Krista M. Heinonen et al.   PLoS One

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

(2010) Laura L. Yates et al.   HUMAN MOLECULAR GENETICS

Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B

(2010) Bing Wang et al.   HUMAN MOLECULAR GENETICS

CIN85/RukLIs a Novel Binding Partner of Nephrin and Podocin and Mediates Slit Diaphragm Turnover in Podocytes

(2010) Irini Tossidou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant Regulation of Planar Cell Polarity in Polycystic Kidney Disease

(2010) A. Luyten et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Wnt signal transduction pathways

(2010) Yuko Komiya et al.   Organogenesis

Transmembrane Topology of the Mammalian Slc11a2 Iron Transporter

(2009) Maciej Czachorowski et al.   BIOCHEMISTRY

Wnt5a regulates distinct signalling pathways by binding to Frizzled2

(2009) Akira Sato et al.   EMBO JOURNAL

Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration

(2009) Phillip A. Vanlandingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Podocyte aPKC /  Causes Polarity Defects and Nephrotic Syndrome

(2009) T. B. Huber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phosphorylation of Nephrin Triggers Its Internalization by Raft-Mediated Endocytosis

(2009) X.-S. Qin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Wnt/ -Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

(2009) C. Dai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis

(2009) Courtney M Karner et al.   NATURE GENETICS

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

(2008) B ZIMMERMAN et al.   CELLULAR SIGNALLING

Wnt5a Is Required for Endothelial Differentiation of Embryonic Stem Cells and Vascularization via Pathways Involving Both Wnt/β-Catenin and Protein Kinase Cα

(2008) Dong-Hwa Yang et al.   CIRCULATION RESEARCH

Differential Stability of Flamingo Protein Complexes Underlies the Establishment of Planar Polarity

(2008) Helen Strutt et al.   CURRENT BIOLOGY

Development of the renal glomerulus: good neighbors and good fences

(2008) S. E. Quaggin et al.   DEVELOPMENT

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease

(2008) Sakura Saburi et al.   NATURE GENETICS