Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Epiphyseal Cartilage Development through β-Catenin-dependent and -independent Pathways

Transforming growth factor alpha controls the transition from hypertrophic cartilage to bone during endochondral bone growth

(2012) Shirine E. Usmani et al.   BONE

Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development

(2012) Debbie Y Dao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Role of tartrate-resistant acid phosphatase (TRAP) in long bone development

(2012) Michael J.F. Blumer et al.   MECHANISMS OF DEVELOPMENT

Abundant LacZ activity in the absence of Cre expression in the normal and inflamed synovium of adult Col2a1-Cre; ROSA26RLacZ reporter mice

(2012) A.J. Fosang et al.   OSTEOARTHRITIS AND CARTILAGE

Receptor Tyrosine Kinases Activate Canonical WNT/β-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct β-Catenin Phosphorylation

(2012) Pavel Krejci et al.   PLoS One

Wnt signaling in cartilage development and degeneration

(2011) Jang-Soo Chun et al.   BMB Reports

The Critical Role of the Epidermal Growth Factor Receptor in Endochondral Ossification

(2011) Xianrong Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

(2011) E J Mackie et al.   JOURNAL OF ENDOCRINOLOGY

Roles of β-catenin signaling in phenotypic expression and proliferation of articular cartilage superficial zone cells

(2011) Rika Yasuhara et al.   LABORATORY INVESTIGATION

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Advances in osteoclast biology: old findings and new insights from mouse models

(2011) James R. Edwards et al.   Nature Reviews Rheumatology

Complementary interplay between matrix metalloproteinase-9, vascular endothelial growth factor and osteoclast function drives endochondral bone formation

(2010) N. Ortega et al.   Disease Models & Mechanisms

Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy

(2010) Gur Pines et al.   FEBS LETTERS

Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo

(2010) Xianrong Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mitogen-Activated Protein Kinases Promote WNT/ -Catenin Signaling via Phosphorylation of LRP6

(2010) I. Cervenka et al.   MOLECULAR AND CELLULAR BIOLOGY

Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer

(2010) Chien-Hsing Lee et al.   Molecular Cancer

Convergence between Wnt-β-catenin and EGFR signaling in cancer

(2010) Tianhui Hu et al.   Molecular Cancer

EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

(2009) Haitao Ji et al.   MOLECULAR CELL

The Wnt/β-Catenin Pathway Interacts Differentially with PTHrP Signaling to Control Chondrocyte Hypertrophy and Final Maturation

(2009) Xizhi Guo et al.   PLoS One

The EGFR network in bone biology and pathology

(2009) Marlon R. Schneider et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Structure, formation and role of cartilage canals in the developing bone

(2008) Michael J.F. Blumer et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Matrix metalloproteinases and bone

(2008) Stephen M. Krane et al.   BONE