H2O2Regulates Lung Epithelial Sodium Channel (ENaC) via Ubiquitin-like Protein Nedd8

The Bacterial Fermentation Product Butyrate Influences Epithelial Signaling via Reactive Oxygen Species-Mediated Changes in Cullin-1 Neddylation

(2014) A. Kumar et al.   JOURNAL OF IMMUNOLOGY

Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung

(2011) Ahmed Lazrak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Nadph oxidase regulates alveolar epithelial sodium channel activity and lung fluid balance in vivo via O2− signaling

(2011) Preston Goodson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation of Alveolar Epithelial Na+Channels by ERK1/2 in Chlorine-Breathing Mice

(2011) Ahmed Lazrak et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Atomic Force Microscopy Reveals the Architecture of the Epithelial Sodium Channel (ENaC)

(2011) Andrew P. Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na+ transport in response to apical fluid volume expansion in human H441 airway epithelial cells

(2011) Chong D. Tan et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Rac1-mediated NADPH oxidase release of O2− regulates epithelial sodium channel activity in the alveolar epithelium

(2010) Yoshizumi Takemura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction

(2010) Daming Gao et al.   MOLECULAR CELL

Interaction of Serum- and Glucocorticoid Regulated Kinase 1 (SGK1) with the WW-Domains of Nedd4-2 Is Required for Epithelial Sodium Channel Regulation

(2010) Dominik Wiemuth et al.   PLoS One

Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1

(2010) Daming Gao et al.   Protein & Cell

IL-1β-induced cortisol stimulates lung fluid absorption in fetal guinea pigs via SGK-mediated Nedd4-2 inhibition

(2009) Tianbo Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

(2009) Thomas R. Kleyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Lipopolysaccharide modifies amiloride-sensitive Na+ transport processes across human airway cells: role of mitogen-activated protein kinases ERK 1/2 and 5

(2009) D. L. Baines et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Activation of the Epithelial Sodium Channel (ENaC) by Serine Proteases

(2008) Bernard C. Rossier et al.   Annual Review of Physiology

Insight toward epithelial Na+channel mechanism revealed by the acid-sensing ion channel 1 structure

(2008) James D. Stockand et al.   IUBMB LIFE

Nedd4-2 Induces Endocytosis and Degradation of Proteolytically Cleaved Epithelial Na+Channels

(2008) Rajesh Kabra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Regulation of Epithelial Sodium Channels Examined in Alveolar Type 1 and 2 Cells Patch-clamped in Lung Slice Tissue

(2008) My N. Helms et al.   JOURNAL OF BIOLOGICAL CHEMISTRY