Structural Basis for Inflammation-driven Shedding of CD163 Ectodomain and Tumor Necrosis Factor-α in Macrophages

Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates

(2013) Roma Stawikowska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-point Electrostatic Receptor-Ligand Pairing

(2013) Marianne Jensby Nielsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging

(2013) Jens Haugbølle Thomsen et al.   Oxidative Medicine and Cellular Longevity

CD163 and Inflammation: Biological, Diagnostic, and Therapeutic Aspects

(2012) Anders Etzerodt et al.   ANTIOXIDANTS & REDOX SIGNALING

Plasma Clearance of Hemoglobin and Haptoglobin in Mice and Effect of CD163 Gene Targeting Disruption

(2012) Anders Etzerodt et al.   ANTIOXIDANTS & REDOX SIGNALING

Soluble CD163 promotes recognition, phagocytosis and killing of Staphylococcus aureus via binding of specific fibronectin peptides

(2012) Jessica Kneidl et al.   CELLULAR MICROBIOLOGY

Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163

(2012) Anders Etzerodt et al.   JOURNAL OF CONTROLLED RELEASE

Comparative assessment of the recognition of domain-specific CD163 monoclonal antibodies in human monocytes explains wide discrepancy in reported levels of cellular surface CD163 expression

(2011) Maciej Bogdan Maniecki et al.   IMMUNOBIOLOGY

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

(2011) Christoph Garbers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble CD163

(2011) Holger J. Møller   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

ADAM17: a molecular switch to control inflammation and tissue regeneration

(2011) Jürgen Scheller et al.   TRENDS IN IMMUNOLOGY

ADAM-17: the enzyme that does it all

(2010) Monika Gooz   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

(2010) Athena Chalaris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor necrosis factor α-converting enzyme (TACE/ADAM17) mediates ectodomain shedding of the scavenger receptor CD163

(2010) Anders Etzerodt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

(2009) Cristina I. Caescu et al.   BIOCHEMICAL JOURNAL

Soluble macrophage-derived CD163: A homogenous ectodomain protein with a dissociable haptoglobin–hemoglobin binding

(2009) Holger Jon Møller et al.   IMMUNOBIOLOGY

Proteomic profiling of human plasma exosomes identifies PPARγ as an exosome-associated protein

(2008) Christopher Looze et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Haptoglobin-Hemoglobin Receptor Conveys Innate Immunity to Trypanosoma brucei in Humans

(2008) B. Vanhollebeke et al.   SCIENCE