Transient Receptor Potential Channel 6 (TRPC6) Protects Podocytes during Complement-mediated Glomerular Disease

NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex

(2013) Eun Young Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol

(2013) Marc Anderson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Gain-of-function Mutations in Transient Receptor Potential C6 (TRPC6) Activate Extracellular Signal-regulated Kinases 1/2 (ERK1/2)

(2013) David Chiluiza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pathogenesis of membranous nephropathy

(2012) Richard J. Glassock   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Angiotensin II Contributes to Podocyte Injury by Increasing TRPC6 Expression via an NFAT-Mediated Positive Feedback Signaling Pathway

(2011) Tom Nijenhuis et al.   AMERICAN JOURNAL OF PATHOLOGY

TRPC6 Enhances Angiotensin II-induced Albuminuria

(2011) J. Eckel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Early-Childhood Membranous Nephropathy Due to Cationic Bovine Serum Albumin

(2011) Hanna Debiec et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Pathogenesis of Idiopathic Membranous Nephropathy: A 50-Year Odyssey

(2010) Richard J. Glassock   AMERICAN JOURNAL OF KIDNEY DISEASES

Toward the development of podocyte-specific drugs

(2010) Jochen Reiser et al.   KIDNEY INTERNATIONAL

Podocyte-Specific Overexpression of Wild Type or Mutant Trpc6 in Mice Is Sufficient to Cause Glomerular Disease

(2010) Paola Krall et al.   PLoS One

TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription

(2009) Johannes Schlöndorff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Compartmentalized signalling: Ca2+ compartments, microdomains and the many facets of Ca2+ signalling

(2009) Alex J. Laude et al.   FEBS Journal

Podocyte Glutamatergic Signaling Contributes to the Function of the Glomerular Filtration Barrier

(2009) L. Giardino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of CaMKII In vivo: The Importance of Targeting and the Intracellular Microenvironment

(2009) Kathryn A. Skelding et al.   NEUROCHEMICAL RESEARCH

M-Type Phospholipase A2Receptor as Target Antigen in Idiopathic Membranous Nephropathy

(2009) Laurence H. Beck et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Novel TRPC6 Mutation That Causes Childhood FSGS

(2009) Saskia F. Heeringa et al.   PLoS One

Therapeutic targets in focal and segmental glomerulosclerosis

(2008) Peter J Lavin et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Sensitizing the Slit Diaphragm with TRPC6 Ion Channels

(2008) C. C. Moller et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

(2008) Christian Faul et al.   NATURE MEDICINE