Fragmented Inositol 1,4,5-Trisphosphate Receptors Retain Tetrameric Architecture and Form Functional Ca2+Release Channels

Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release

(2012) Askar M. Akimzhanov et al.   CELL CALCIUM

Identification of Functionally Critical Residues in the Channel Domain of Inositol Trisphosphate Receptors

(2012) Cunnigaiper Bhanumathy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis

(2012) Ghadi Elkoreh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor impairs ER Ca2+buffering and causes neurodegeneration in primary cortical neurons

(2012) Catherine M. Kopil et al.   JOURNAL OF NEUROCHEMISTRY

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

(2012) Min-Duk Seo et al.   NATURE

Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis

(2012) K. Shimbo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calpain-cleaved Type 1 Inositol 1,4,5-Trisphosphate Receptor (InsP3R1) Has InsP3-independent Gating and Disrupts Intracellular Ca2+Homeostasis

(2011) Catherine M. Kopil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flexible Architecture of IP3R1 by Cryo-EM

(2011) Steven J. Ludtke et al.   STRUCTURE

The IP3 receptor–mitochondria connection in apoptosis and autophagy

(2010) Jean-Paul Decuypere et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Linking structure to function: Recent lessons from inositol 1,4,5-trisphosphate receptor mutagenesis

(2010) David I. Yule et al.   CELL CALCIUM

Intracellular Ca2+ storage in health and disease: A dynamic equilibrium

(2010) Eva Sammels et al.   CELL CALCIUM

Structural Studies of Inositol 1,4,5-Trisphosphate Receptor

(2010) Jenny Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyr-167/Trp-168 in Type 1/3 Inositol 1,4,5-Trisphosphate Receptor Mediates Functional Coupling between Ligand Binding and Channel Opening

(2010) Haruka Yamazaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tethering Function of the Caspase Cleavage Fragment of Golgi Protein p115 Promotes Apoptosis via a p53-dependent Pathway

(2010) Poh Choo How et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apoptosis and Autophagy: Decoding Calcium Signals that Mediate Life or Death

(2010) M. W. Harr et al.   Cold Spring Harbor Perspectives in Biology

IP3receptors: some lessons from DT40 cells

(2009) Colin W. Taylor et al.   IMMUNOLOGICAL REVIEWS

ATP Regulation of Type-1 Inositol 1,4,5-Trisphosphate Receptor Activity Does Not Require Walker A-type ATP-binding Motifs

(2009) Matthew J. Betzenhauser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase A Increases Type-2 Inositol 1,4,5-Trisphosphate Receptor Activity by Phosphorylation of Serine 937

(2009) Matthew J. Betzenhauser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inositol trisphosphate and calcium signalling mechanisms

(2008) Michael J. Berridge   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Characterization of β-N-Acetylglucosaminidase Cleavage by Caspase-3 during Apoptosis

(2008) Chutikarn Butkinaree et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP Modulation of Ca2+Release by Type-2 and Type-3 Inositol (1, 4, 5)-Triphosphate Receptors

(2008) Matthew J. Betzenhauser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass Spectrometric Analysis of Type 1 Inositol 1,4,5-Trisphosphate Receptor Ubiquitination

(2008) Danielle A. Sliter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Studying isoform-specific inositol 1,4,5-trisphosphate receptor function and regulation

(2008) Matthew J. Betzenhauser et al.   METHODS

Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca2+ leak and disturbs Ca2+ signalling

(2007) Leen Verbert et al.   BIOLOGY OF THE CELL