Retinoic Acid-related Orphan Receptor α Regulates Diurnal Rhythm and Fasting Induction of Sterol 12α-Hydroxylase in Bile Acid Synthesis

Impaired Generation of 12-Hydroxylated Bile Acids Links Hepatic Insulin Signaling with Dyslipidemia

(2011) Rebecca A. Haeusler et al.   Cell Metabolism

Glucose and Insulin Induction of Bile Acid Synthesis

(2011) Tiangang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional profiling reveals a role for RORα in regulating gene expression in obesity-associated inflammation and hepatic steatosis

(2011) Hong Soon Kang et al.   PHYSIOLOGICAL GENOMICS

Diurnal Variations of Mouse Plasma and Hepatic Bile Acid Concentrations as well as Expression of Biosynthetic Enzymes and Transporters

(2011) Yu-Kun Jennifer Zhang et al.   PLoS One

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Transgenic expression of cholesterol 7α-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice

(2010) Tiangang Li et al.   HEPATOLOGY

Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism

(2010) Gemma Brufau et al.   HEPATOLOGY

Characterization of the Core Mammalian Clock Component, NPAS2, as a REV-ERBα/RORα Target Gene

(2010) Christine Crumbley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

(2010) Thijs W.H. Pols et al.   JOURNAL OF HEPATOLOGY

Abolished synthesis of cholic acid reduces atherosclerotic development in apolipoprotein E knockout mice

(2010) Katharina Slätis et al.   JOURNAL OF LIPID RESEARCH

Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice

(2010) Youcai Zhang et al.   JOURNAL OF LIPID RESEARCH

A Novel Bile Acid-Activated Vitamin D Receptor Signaling in Human Hepatocytes

(2010) Shuxin Han et al.   MOLECULAR ENDOCRINOLOGY

Forkhead box transcription factor O1 inhibits cholesterol 7α-hydroxylase in human hepatocytes and in high fat diet-fed mice

(2009) Tiangang Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands

(2009) Yongjun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Mechanism of Vitamin D Receptor Inhibition of Cholesterol 7 -Hydroxylase Gene Transcription in Human Hepatocytes

(2008) S. Han et al.   DRUG METABOLISM AND DISPOSITION

Regulation of Bile Acid Synthesis by the Nuclear Receptor Rev-erbα

(2008) Hélène Duez et al.   GASTROENTEROLOGY

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY