Runx2 Protein Represses Axin2 Expression in Osteoblasts and Is Required for Craniosynostosis inAxin2-deficient Mice

Histone deacetylase 3 is required for maintenance of bone mass during aging

(2012) Meghan E. McGee-Lawrence et al.   BONE

Prevention of Premature Fusion of Calvarial Suture in GLI-Kruppel Family Member 3 (Gli3)-deficient Mice by Removing One Allele of Runt-related Transcription Factor 2 (Runx2)

(2012) Yukiho Tanimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects

(2011) Takafumi Maeno et al.   BONE

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts

(2011) Meghan E. McGee-Lawrence et al.   BONE

Craniosynostosis

(2011) David Johnson et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Functional characterization of a novel FGFR2 mutation, E731K, in craniosynostosis

(2011) Jounghyen Park et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TIEG1/KLF10 Modulates Runx2 Expression and Activity in Osteoblasts

(2011) John R. Hawse et al.   PLoS One

Craniosynostosis of Coronal Suture in Twist1+/− Mice Occurs Through Endochondral Ossification Recapitulating the Physiological Closure of Posterior Frontal Suture

(2011) Björn Behr et al.   Frontiers in Physiology

Copy number variation analysis in single-suture craniosynostosis: Multiple rare variants including RUNX2 duplication in two cousins with metopic craniosynostosis

(2010) Heather C. Mefford et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

β-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis

(2010) Anthony J Mirando et al.   BMC DEVELOPMENTAL BIOLOGY

HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling

(2010) Cassandra A. Godman et al.   CANCER BIOLOGY & THERAPY

Beyond the closed suture in apert syndrome mouse models: Evidence of primary effects of FGFR2 signaling on facial shape at birth

(2010) Neus Martínez-Abadías et al.   DEVELOPMENTAL DYNAMICS

Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation

(2010) D. P. C. Rice et al.   HUMAN MOLECULAR GENETICS

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity

(2010) Eric Hesse et al.   JOURNAL OF CELL BIOLOGY

Prevalence and Complications of Single-Gene and Chromosomal Disorders in Craniosynostosis

(2010) A. O. M. Wilkie et al.   PEDIATRICS

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

(2010) David F. Razidlo et al.   PLoS One

The Balance of WNT and FGF Signaling Influences Mesenchymal Stem Cell Fate During Skeletal Development

(2010) T. Maruyama et al.   Science Signaling

Wnt Proteins Promote Bone Regeneration

(2010) S. Minear et al.   Science Translational Medicine

Axin2 controls bone remodeling through the  -catenin-BMP signaling pathway in adult mice

(2009) Y. Yan et al.   JOURNAL OF CELL SCIENCE

Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors

(2009) Xiaodong Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

(2009) J Akech et al.   ONCOGENE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

A population-based study of craniosynostosis in metropolitan Atlanta, 1989–2003

(2008) Sheree L. Boulet et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

(2008) J. Pratap et al.   CANCER RESEARCH

A Runx2 threshold for the cleidocranial dysplasia phenotype

(2008) Y. Lou et al.   HUMAN MOLECULAR GENETICS

The Boston-type Craniosynostosis Mutation MSX2 (P148H) Results in Enhanced Susceptibility of MSX2 to Ubiquitin-dependent Degradation

(2008) Won-Joon Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY