LKB1 Represses Focal Adhesion Kinase (FAK) Signaling via a FAK-LKB1 Complex to Regulate FAK Site Maturation and Directional Persistence

LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin

(2013) David B. Shackelford et al.   CANCER CELL

LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity

(2012) Xiaojian Xu et al.   BMC CELL BIOLOGY

The CRTC1-NEDD9 Signaling Axis Mediates Lung Cancer Progression Caused by LKB1 Loss

(2012) Y. Feng et al.   CANCER RESEARCH

STE20-related Kinase Adaptor Protein α (STRADα) Regulates Cell Polarity and Invasion through PAK1 Signaling in LKB1-null Cells

(2012) Carrie M. Eggers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration

(2012) Praveen Suraneni et al.   JOURNAL OF CELL BIOLOGY

Focal adhesion kinase modulates Cdc42 activity downstream of positive and negative axon guidance cues

(2012) Jonathan P. Myers et al.   JOURNAL OF CELL SCIENCE

AMPK Regulates Mitotic Spindle Orientation through Phosphorylation of Myosin Regulatory Light Chain

(2012) J. T. Thaiparambil et al.   MOLECULAR AND CELLULAR BIOLOGY

Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

(2011) Jose T. Thaiparambil et al.   INTERNATIONAL JOURNAL OF CANCER

Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung Tumors

(2010) Julian Carretero et al.   CANCER CELL

Knock-in Mutation Reveals an Essential Role for Focal Adhesion Kinase Activity in Blood Vessel Morphogenesis and Cell Motility-Polarity but Not Cell Proliferation

(2010) Ssang-Taek Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell biology of the movement of breast cancer cells: Intracellular signalling and the actin cytoskeleton

(2009) Ping Jiang et al.   CANCER LETTERS

L1 cell adhesion molecule (L1CAM) in invasive tumors

(2009) Shani Raveh et al.   CANCER LETTERS

Vascular Cell Adhesion Molecule-1 Is a Regulator of Ovarian Cancer Peritoneal Metastasis

(2009) Jill K. Slack-Davis et al.   CANCER RESEARCH

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of the LKB1-STRAD-MO25 Complex Reveals an Allosteric Mechanism of Kinase Activation

(2009) E. Zeqiraj et al.   SCIENCE

A Novel Gene Expression Profile in Lymphatics Associated with Tumor Growth and Nodal Metastasis

(2008) S. Clasper et al.   CANCER RESEARCH

The Tumor Suppressor LKB1 Regulates Lung Cancer Cell Polarity by Mediating cdc42 Recruitment and Activity

(2008) S. Zhang et al.   CANCER RESEARCH

Src activation and translocation from focal adhesions to membrane ruffles contribute to formation of new adhesion sites

(2008) A. Hamadi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Overexpression of HAb18G/CD147 promotes invasion and metastasis via α3β1 integrin mediated FAK-paxillin and FAK-PI3K-Ca2+ pathways

(2008) J. Tang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices

(2008) A. Nobumoto et al.   GLYCOBIOLOGY

Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferation

(2008) Paul Fiorilli et al.   LABORATORY INVESTIGATION

2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition

(2008) D. Zhong et al.   MOLECULAR CANCER THERAPEUTICS

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Polarity proteins in migration and invasion

(2008) S Etienne-Manneville   ONCOGENE