Enhanced Phosphatidylinositol 3-kinase (PI3K)/Akt Signaling Has Pleiotropic Targets in Hippocampal Neurons Exposed to Iron-induced Oxidative Stress

Distinctive roles of PLD signaling elicited by oxidative stress in synaptic endings from adult and aged rats

(2012) Melina V. Mateos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Wnt1 Inducible Signaling Pathway Protein 1 (WISP1) Blocks Neurodegeneration through Phosphoinositide 3 Kinase/Akt1 and Apoptotic Mitochondrial Signaling Involving Bad, Bax, Bim, and Bcl-xL

(2012) Shaohui Wang et al.   CURRENT NEUROVASCULAR RESEARCH

The Akt-FoxO3a-manganese superoxide dismutase pathway is involved in the regulation of oxidative stress in diabetic nephropathy

(2012) Qian Lu et al.   EXPERIMENTAL PHYSIOLOGY

Metallostasis in Alzheimer's disease

(2012) Scott Ayton et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ubiquitin-dependent Regulation of Phospho-AKT Dynamics by the Ubiquitin E3 Ligase, NEDD4-1, in the Insulin-like Growth Factor-1 Response

(2012) Chuan-Dong Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Excess iron harms the brain: the syndromes of neurodegeneration with brain iron accumulation (NBIA)

(2012) Susanne A. Schneider et al.   JOURNAL OF NEURAL TRANSMISSION

Differential participation of phospholipase A2 isoforms during iron-induced retinal toxicity. Implications for age-related macular degeneration

(2012) G. Rodríguez Diez et al.   NEUROCHEMISTRY INTERNATIONAL

Metals, oxidative stress and neurodegeneration: A focus on iron, manganese and mercury

(2012) Marcelo Farina et al.   NEUROCHEMISTRY INTERNATIONAL

Coenzyme Q10 protects against amyloid beta-induced neuronal cell death by inhibiting oxidative stress and activating the P13K pathway

(2011) Hojin Choi et al.   NEUROTOXICOLOGY

Downregulation of Manganese Superoxide Dismutase by Angiotensin II in Cardiac Fibroblasts of Rats: Association With Oxidative Stress in Myocardium

(2010) Paul J. Lijnen et al.   AMERICAN JOURNAL OF HYPERTENSION

Subcellular Localization of Activated AKT in Estrogen Receptor- and Progesterone Receptor-Expressing Breast Cancers

(2010) Sunil Badve et al.   AMERICAN JOURNAL OF PATHOLOGY

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples

(2010) Douglas B. Kell   ARCHIVES OF TOXICOLOGY

Iron in neuronal function and dysfunction

(2010) Gabriela A. Salvador   BIOFACTORS

Effect of transition metals in synaptic damage induced by amyloid beta peptide

(2010) R.M. Uranga et al.   NEUROSCIENCE

Switching Akt: from survival signaling to deadly response

(2009) Marek Los et al.   BIOESSAYS

Cilnidipine mediates a neuroprotective effect by scavenging free radicals and activating the phosphatidylinositol 3-kinase pathway

(2009) Young Joo Lee et al.   JOURNAL OF NEUROCHEMISTRY

Iron accumulation in syndromes of neurodegeneration with brain iron accumulation 1 and 2: causative or consequential?

(2009) S A Schneider et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

(2009) Bo Su et al.   Molecular Neurodegeneration

Iron-Induced Oxidative Injury Differentially Regulates PI3K/Akt/GSK3β Pathway in Synaptic Endings from Adult and Aged Rats

(2009) Romina María Uranga et al.   TOXICOLOGICAL SCIENCES

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Regulation of Neuronal Glutathione Synthesis

(2008) Koji Aoyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Activation of phosphatidylcholine signalling during oxidative stress in synaptic endings

(2008) Melina V. Mateos et al.   NEUROCHEMISTRY INTERNATIONAL

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK

(2008) K. A. Boehme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA