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Title
γ-Secretase Associated with Lipid Rafts
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 8, Pages 5109-5121
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2013-12-29
DOI
10.1074/jbc.m113.510131
References
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Related references
Note: Only part of the references are listed.- Palmitoylation of Amyloid Precursor Protein Regulates Amyloidogenic Processing in Lipid Rafts
- (2013) R. Bhattacharyya et al. JOURNAL OF NEUROSCIENCE
- γ-Secretase Modulators and Presenilin 1 Mutants Act Differently on Presenilin/γ-Secretase Function to Cleave Aβ42 and Aβ43
- (2013) Masayasu Okochi et al. Cell Reports
- Presenilins and -Secretase: Structure, Function, and Role in Alzheimer Disease
- (2013) B. De Strooper et al. Cold Spring Harbor Perspectives in Medicine
- The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
- (2012) Lucía Chávez-Gutiérrez et al. EMBO JOURNAL
- The Backbone Dynamics of the Amyloid Precursor Protein Transmembrane Helix Provides a Rationale for the Sequential Cleavage Mechanism of γ-Secretase
- (2012) Oxana Pester et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure of a presenilin family intramembrane aspartate protease
- (2012) Xiaochun Li et al. NATURE
- Phenylpiperidine-type γ-secretase modulators target the transmembrane domain 1 of presenilin 1
- (2011) Yu Ohki et al. EMBO JOURNAL
- Potent amyloidogenicity and pathogenicity of Aβ43
- (2011) Takashi Saito et al. NATURE NEUROSCIENCE
- Membrane rafts in Alzheimer's disease beta-amyloid production
- (2010) Kulandaivelu S. Vetrivel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Three-Amino Acid Spacing of Presenilin Endoproteolysis Suggests a General Stepwise Cleavage of -Secretase-Mediated Intramembrane Proteolysis
- (2010) A. Fukumori et al. JOURNAL OF NEUROSCIENCE
- Alzheimer's disease: clinical trials and drug development
- (2010) Francesca Mangialasche et al. LANCET NEUROLOGY
- -Secretase: Successive Tripeptide and Tetrapeptide Release from the Transmembrane Domain of -Carboxyl Terminal Fragment
- (2009) M. Takami et al. JOURNAL OF NEUROSCIENCE
- A novel pathway for amyloid precursor protein processing
- (2009) Erik Portelius et al. NEUROBIOLOGY OF AGING
- Effects of γ-Secretase Inhibition on the Amyloid β Isoform Pattern in a Mouse Model of Alzheimer’s Disease
- (2009) Erik Portelius et al. Neurodegenerative Diseases
- A helix-to-coil transition at the -cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis
- (2009) T. Sato et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toward Structural Elucidation of the γ-Secretase Complex
- (2009) Huilin Li et al. STRUCTURE
- Active γ-secretase is localized to detergent-resistant membranes in human brain
- (2008) Ji-Yeun Hur et al. FEBS Journal
- Independent Generation of Aβ42 and Aβ38 Peptide Species by γ-Secretase
- (2008) Eva Czirr et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct and Potent Regulation of γ-Secretase by Its Lipid Microenvironment
- (2008) Pamela Osenkowski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
- (2003) H. F. Dovey et al. JOURNAL OF NEUROCHEMISTRY
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