Rapamycin Induces Mitogen-activated Protein (MAP) Kinase Phosphatase-1 (MKP-1) Expression through Activation of Protein Kinase B and Mitogen-activated Protein Kinase Kinase Pathways

Involvement of MAPK Phosphatase-1 in Dexamethasone-Induced Chemoresistance in Lung Cancer

(2014) Jian Huang et al.   JOURNAL OF CHEMOTHERAPY

Resolution of Chylous Pulmonary Congestion and Respiratory Failure in Lymphangioleiomyomatosis with Sirolimus Therapy

(2013) Teng Moua et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways

(2013) Jiyeon S Kim et al.   NATURE IMMUNOLOGY

ATF2 – at the crossroad of nuclear and cytosolic functions

(2012) Eric Lau et al.   JOURNAL OF CELL SCIENCE

TLR4-Mediated AKT Activation Is MyD88/TRIF Dependent and Critical for Induction of Oxidative Phosphorylation and Mitochondrial Transcription Factor A in Murine Macrophages

(2012) C. P. Bauerfeld et al.   JOURNAL OF IMMUNOLOGY

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian Target of Rapamycin Complex 2 (mTORC2) Negatively Regulates Toll-like Receptor 4-mediated Inflammatory Response via FoxO1

(2011) Jonathan Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapamycin Attenuates Airway Hyperreactivity, Goblet Cells, and IgE in Experimental Allergic Asthma

(2011) E. M. Mushaben et al.   JOURNAL OF IMMUNOLOGY

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

Dysregulation of p38 and MKP-1 in Response to NOD1/TLR4 Stimulation in Sarcoid Bronchoalveolar Cells

(2010) Ruchi Rastogi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

cAMP-response Element-binding Protein (CREB) Controls MSK1-mediated Phosphorylation of Histone H3 at the c-fosPromoterin Vitro

(2010) Miho Shimada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Modification of Nuclear Mitogen-activated Protein Kinase Phosphatase 1 Is Involved in Transforming Growth Factor β1-induced Expression of Plasminogen Activator Inhibitor 1 in Fibroblasts

(2010) Rui-Ming Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-talk between the p38α and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation

(2010) Christopher J. Staples et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 3-Kinase Activation Attenuates the TLR2-Mediated Macrophage Proinflammatory Cytokine Response to Francisella tularensis Live Vaccine Strain

(2010) E. A. Medina et al.   JOURNAL OF IMMUNOLOGY

Anti-inflammatory properties of the PI3K pathway are mediated by IL-10/DUSP regulation

(2010) Philipp Günzl et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mkp1 Is a c-Jun Target Gene That Antagonizes JNK-Dependent Apoptosis in Sympathetic Neurons

(2010) M. Kristiansen et al.   JOURNAL OF NEUROSCIENCE

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MKP-1 Is Necessary for T Cell Activation and Function

(2009) Yongliang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria

(2009) Lobelia Samavati et al.   MOLECULAR IMMUNOLOGY

A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal

(2009) Federica Catalanotti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rapamycin induces transactivation of the EGFR and increases cell survival

(2009) D Chaturvedi et al.   ONCOGENE

Immune Regulation by Rapamycin: Moving Beyond T Cells

(2009) M. R. Janes et al.   Science Signaling

The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response

(2008) Thomas Weichhart et al.   IMMUNITY

Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP

(2008) Krishan Johansson-Haque et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The role of MAP kinase phosphatase-1 in the protective mechanism of dexamethasone against endotoxemia

(2008) Xianxi Wang et al.   LIFE SCIENCES

MKP-1 mRNA Stabilization and Translational Control by RNA-Binding Proteins HuR and NF90

(2008) Y. Kuwano et al.   MOLECULAR AND CELLULAR BIOLOGY

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

(2008) Olga Ananieva et al.   NATURE IMMUNOLOGY

Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

(2008) Weiping Cao et al.   NATURE IMMUNOLOGY