Retinitis Pigmentosa Mutants Provide Insight into the Role of the N-terminal Cap in Rhodopsin Folding, Structure, and Function

Rhodopsin Mutant P23H Destabilizes Rod Photoreceptor Disk Membranes

(2012) Mohammad Haeri et al.   PLoS One

Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa

(2011) Laia Bosch-Presegué et al.   FEBS Journal

Rescue of expression and signaling of human luteinizing hormone G protein-coupled receptor mutants with an allosterically binding small-molecule agonist

(2011) C. L. Newton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Activation of the Visual Pigment Rhodopsin

(2010) Steven O. Smith   Annual Review of Biophysics

Structural insights into retinitis pigmentosa from unfolding simulations of rhodopsin mutants

(2010) Francesca Fanelli et al.   FASEB JOURNAL

Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation

(2010) M.C. Peeters et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Molecular Mechanisms of Rhodopsin Retinitis Pigmentosa and the Efficacy of Pharmacological Rescue

(2009) Mark P. Krebs et al.   JOURNAL OF MOLECULAR BIOLOGY

Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation

(2009) Shivani Ahuja et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A G protein-coupled receptor at work: the rhodopsin model

(2009) Klaus Peter Hofmann et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY