A Novel p53 Mutant Found in Iatrogenic Urothelial Cancers Is Dysfunctional and Can Be Rescued by a Second-site Global Suppressor Mutation

Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid

(2013) M. Hollstein et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

Efficient introduction of specific TP53 mutations into mouse embryonic fibroblasts and embryonic stem cells

(2012) Quan-Xiang Wei et al.   Nature Protocols

Tumor suppressor p53 (TP53) at the crossroads of the exposome and the cancer genome

(2012) A. J. Schetter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aristolochic acid-associated urothelial cancer in Taiwan

(2012) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specificTrp53platform

(2011) Quan-Xiang Wei et al.   CELL CYCLE

Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights

(2010) Assia Merabet et al.   BIOCHEMICAL JOURNAL

Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing

(2010) Ahmad Besaratinia et al.   FASEB JOURNAL

Wild-type and Hupki (Human p53 Knock-in) Murine Embryonic Fibroblasts

(2010) Catherine Whibley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Tumor Suppressor p53: From Structures to Drug Discovery

(2010) A. C. Joerger et al.   Cold Spring Harbor Perspectives in Biology

Population-Based Case-Control Study of Chinese Herbal Products Containing Aristolochic Acid and Urinary Tract Cancer Risk

(2009) M.-N. Lai et al.   JNCI-Journal of the National Cancer Institute

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

Predicting Positive p53 Cancer Rescue Regions Using Most Informative Positive (MIP) Active Learning

(2009) Samuel A. Danziger et al.   PLoS Computational Biology

TP53mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours

(2008) Tatiana Nedelko et al.   INTERNATIONAL JOURNAL OF CANCER