The HECT Type Ubiquitin Ligase NEDL2 Is Degraded by Anaphase-promoting Complex/Cyclosome (APC/C)-Cdh1, and Its Tight Regulation Maintains the Metaphase to Anaphase Transition

The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth

(2012) M. Kannan et al.   DEVELOPMENT

Lamin misexpression upregulates three distinct ubiquitin ligase systems that degrade ATR kinase in HeLa cells

(2012) Bhattiprolu Muralikrishna et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

p250GAP Is a Novel Player in the Cdh1-APC/Smurf1 Pathway of Axon Growth Regulation

(2012) Madhuvanthi Kannan et al.   PLoS One

Muscle Atrophy and Motor Neuron Degeneration in Human NEDL1 Transgenic Mice

(2010) Lin Zhang et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Streamlined analysis schema for high-throughput identification of endogenous protein complexes

(2010) A. Malovannaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Skp2-p27 Axis by the Cdh1/Anaphase-Promoting Complex Pathway in Colorectal Tumorigenesis

(2008) Takeo Fujita et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of APC/C Activators in Mitosis and Meiosis

(2008) Jillian A. Pesin et al.   Annual Review of Cell and Developmental Biology

The Aneuploidy Paradox in Cell Growth and Tumorigenesis

(2008) Beth A. Weaver et al.   CANCER CELL

The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint

(2008) Evan C. Osmundson et al.   JOURNAL OF CELL BIOLOGY

A novel HECT-type E3 ubiquitin protein ligase NEDL1 enhances the p53-mediated apoptotic cell death in its catalytic activity-independent manner

(2008) Y Li et al.   ONCOGENE