LRP1 Assembles Unique Co-receptor Systems to Initiate Cell Signaling in Response to Tissue-type Plasminogen Activator and Myelin-associated Glycoprotein

Low Density Lipoprotein Receptor-related Protein 1 (LRP1) ModulatesN-Methyl-d-aspartate (NMDA) Receptor-dependent Intracellular Signaling and NMDA-induced Regulation of Postsynaptic Protein Complexes

(2013) Chikako Nakajima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes

(2012) B. Niego et al.   BLOOD

Identification of the Low Density Lipoprotein (LDL) Receptor-related Protein-1 Interactome in Central Nervous System Myelin Suggests a Role in the Clearance of Necrotic Cell Debris

(2012) Anthony Fernandez-Castaneda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin

(2012) Travis L. Stiles et al.   JOURNAL OF CELL SCIENCE

Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK1/2–CREB–ATF3 signaling pathway

(2012) Fang Wu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Axonal Regrowth after Spinal Cord Injury via Chondroitinase and the Tissue Plasminogen Activator (tPA)/Plasmin System

(2011) N. Bukhari et al.   JOURNAL OF NEUROSCIENCE

Tissue-type plasminogen activator induces plasmin-dependent proteolysis of intracellular neuronal nitric oxide synthase

(2010) Amandine Baron et al.   BIOLOGY OF THE CELL

Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus

(2010) Ramiro Echeverry et al.   JOURNAL OF CLINICAL INVESTIGATION

A non-muscle myosin II motor links NR1 to retrograde trafficking and proteasomal degradation in PC12 cells

(2010) Rema Vazhappilly et al.   NEUROCHEMISTRY INTERNATIONAL

Low Density Lipoprotein Receptor-related Protein 1 Promotes Anti-apoptotic Signaling in Neurons by Activating Akt Survival Pathway

(2009) Rodrigo A. Fuentealba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nontraditional Signaling Mechanisms of Lipoprotein Receptors

(2009) G. W. Rebeck   Science Signaling

Ligand Binding to LRP1 Transactivates Trk Receptors by a Src Family Kinase-Dependent Pathway

(2009) Y. Shi et al.   Science Signaling

The Functional Role of the Second NPXY Motif of the LRP1 β-Chain in Tissue-type Plasminogen Activator-mediated Activation ofN-Methyl-D-aspartate Receptors

(2008) Anne M. Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Dissection of the Human α2-Macroglobulin Subunit Reveals Domains with Antagonistic Activities in Cell Signaling

(2008) Elisabetta Mantuano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-methyl-d-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein

(2008) Zhenyu Sheng et al.   NEUROPHARMACOLOGY

Caveolin-1 expression is essential for N-methyl-d-aspartate receptor-mediated Src and extracellular signal-regulated kinase 1/2 activation and protection of primary neurons from ischemic cell death

(2007) Brian P. Head et al.   FASEB JOURNAL