Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

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Conformational Motions Regulate Phosphoryl Transfer in Related Protein Tyrosine Phosphatases

(2013) S. K. Whittier et al.   SCIENCE

The amphipathic helix of an enzyme that regulates phosphatidylcholine synthesis remodels membranes into highly curved nanotubules

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ras-induced Up-regulation of CTP:Phosphocholine Cytidylyltransferase α Contributes to Malignant Transformation of Intestinal Epithelial Cells

(2012) Daniel J. Arsenault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A 22-mer Segment in the Structurally Pliable Regulatory Domain of Metazoan CTP: Phosphocholine Cytidylyltransferase Facilitates Both Silencing and Activating Functions

(2012) Ziwei Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Membrane-Binding Domain of an Amphitropic Enzyme Suppresses Catalysis by Contact with an Amphipathic Helix Flanking Its Active Site

(2012) Harris K-H. Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

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Overview of theCCP4 suite and current developments

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Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

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Regulation of protein kinases by lipids

(2011) Thomas A Leonard et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Intrinsically Disordered Nuclear Localization Signal and Phosphorylation Segments Distinguish the Membrane Affinity of Two Cytidylyltransferase Isoforms

(2011) Melissa K. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipid Synthesis Participates in the Regulation of Diacylglycerol Required for Membrane Trafficking at the Golgi Complex

(2011) Elisabet Sarri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

R.E.D. Server: a web service for deriving RESP and ESP charges and building force field libraries for new molecules and molecular fragments

(2011) Enguerran Vanquelef et al.   NUCLEIC ACIDS RESEARCH

Protein Kinase C Regulation: C1 Meets C-tail

(2011) Marcelo G. Kazanietz et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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Coupled motions in enzyme catalysis

(2010) Vishal C Nashine et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A role for flexible loops in enzyme catalysis

(2010) M Merced Malabanan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

(2010) Wen-I Wu et al.   PLoS One

SH2 domains: modulators of nonreceptor tyrosine kinase activity

(2009) Panagis Filippakopoulos et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crystal Structure of a Mammalian CTP: Phosphocholine Cytidylyltransferase Catalytic Domain Reveals Novel Active Site Residues within a Highly Conserved Nucleotidyltransferase Fold

(2009) Jaeyong Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New insights into the membrane-binding and activation mechanism of pyruvate oxidase from Escherichia coli

(2009) Annett Weidner et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

Contribution of Each Membrane Binding Domain of the CTP:Phosphocholine Cytidylyltransferase-α Dimer to Its Activation, Membrane Binding, and Membrane Cross-bridging

(2008) Svetla Taneva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from Escherichia coli

(2008) P. Neumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA