SEC14 and Spectrin Domains 1 (Sestd1) and Dapper Antagonist of Catenin 1 (Dact1) Scaffold Proteins Cooperatively Regulate the Van Gogh-like 2 (Vangl2) Four-pass Transmembrane Protein and Planar Cell Polarity (PCP) Pathway during Embryonic Development in Mice

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

(2012) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Identification of novel rare mutations of DACT1 in human neural tube defects

(2012) Yan Shi et al.   HUMAN MUTATION

Planar Cell Polarity and the Developmental Control of Cell Behavior in Vertebrate Embryos

(2011) John B. Wallingford   Annual Review of Cell and Developmental Biology

Human neural tube defects: Genetic causes and prevention

(2011) Patrizia De Marco et al.   BIOFACTORS

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

(2011) Saul Kivimäe et al.   BMC BIOCHEMISTRY

Mutations in the planar cell polarity genesCELSR1andSCRIBare associated with the severe neural tube defect craniorachischisis

(2011) Alexis Robinson et al.   HUMAN MUTATION

Contribution of VANGL2 mutations to isolated neural tube defects

(2010) Z Kibar et al.   CLINICAL GENETICS

Loss of Dact1 Disrupts Planar Cell Polarity Signaling by Altering Dishevelled Activity and Leads to Posterior Malformation in Mice

(2010) Jun Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Phospholipid-binding Protein SESTD1 Is a Novel Regulator of the Transient Receptor Potential Channels TRPC4 and TRPC5

(2010) Susanne Miehe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dact1 Is a Postsynaptic Protein Required for Dendrite, Spine, and Excitatory Synapse Development in the Mouse Forebrain

(2010) N. D. Okerlund et al.   JOURNAL OF NEUROSCIENCE

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

(2010) Hai Song et al.   NATURE

VANGL2Mutations in Human Cranial Neural-Tube Defects

(2010) Yun-Ping Lei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak

(2009) Rowena Suriben et al.   NATURE GENETICS

DACT3 Is an Epigenetic Regulator of Wnt/β-Catenin Signaling in Colorectal Cancer and Is a Therapeutic Target of Histone Modifications

(2008) Xia Jiang et al.   CANCER CELL

Wnt/β-catenin signaling: new (and old) players and new insights

(2008) He Huang et al.   CURRENT OPINION IN CELL BIOLOGY

Dapper1 Is a Nucleocytoplasmic Shuttling Protein That Negatively Modulates Wnt Signaling in the Nucleus

(2008) Xia Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accelerated re-epithelialization in Dpr2-deficient mice is associated with enhanced response to TGF  signaling

(2008) F. Meng et al.   JOURNAL OF CELL SCIENCE