Soluble Ecto-5′-nucleotidase (5′-NT), Alkaline Phosphatase, and Adenosine Deaminase (ADA1) Activities in Neonatal Blood Favor Elevated Extracellular Adenosine

Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities

(2012) Gennady G. Yegutkin et al.   FASEB JOURNAL

Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1–dependent pathways

(2012) Victoria J. Philbin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Neonatal Plasma Polarizes TLR4-Mediated Cytokine Responses towards Low IL-12p70 and High IL-10 Production via Distinct Factors

(2012) Mirjam E. Belderbos et al.   PLoS One

Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities

(2011) Melanie R Power Coombs et al.   Expert Review of Anti-Infective Therapy

Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants

(2011) Sarah Burl et al.   PLoS One

Structural Basis for the Growth Factor Activity of Human Adenosine Deaminase ADA2

(2010) Anton V. Zavialov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TLR2 Mediates Recognition of Live Staphylococcus epidermidis and Clearance of Bacteremia

(2010) Tobias Strunk et al.   PLoS One

Acquisition of Adult-Like TLR4 and TLR9 Responses during the First Year of Life

(2010) Muriel Nguyen et al.   PLoS One

Ontogeny of Toll-Like Receptor Mediated Cytokine Responses of Human Blood Mononuclear Cells

(2010) Nathan P. Corbett et al.   PLoS One

Nucleoside Transporter Proteins

(2009) Miriam Molina-Arcas et al.   Current Vascular Pharmacology

Phenotype and function of neonatal DC

(2009) Fabienne Willems et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Staphylococcus aureussynthesizes adenosine to escape host immune responses

(2009) Vilasack Thammavongsa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

(2009) T. R. Kollmann et al.   JOURNAL OF IMMUNOLOGY

Discovery and Validation of a Series of Aryl Sulfonamides as Selective Inhibitors of Tissue-Nonspecific Alkaline Phosphatase (TNAP)

(2009) Russell Dahl et al.   JOURNAL OF MEDICINAL CHEMISTRY

The P2X7 receptor and intracellular pathogens: a continuing struggle

(2009) Robson Coutinho-Silva et al.   Purinergic Signalling

Extracellular ATP in the Immune System: More Than Just a "Danger Signal"

(2009) A. Trautmann   Science Signaling

Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000

(2009) Zhan-Guo Gao et al.   BMC Pharmacology & Toxicology

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

(2008) Gennady G. Yegutkin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists

(2008) J. L. Wynn et al.   BLOOD

CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation

(2008) Yara Banz et al.   BRITISH JOURNAL OF HAEMATOLOGY

Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function

(2008) Balázs Csóka et al.   FASEB JOURNAL

Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

(2008) Patrizia Pellegatti et al.   PLoS One

Purinergic Control of T Cell Activation by ATP Released Through Pannexin-1 Hemichannels

(2008) U. Schenk et al.   Science Signaling