A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “ARE2Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance

Making, Baking, and Breaking: the Synthesis, Storage, and Hydrolysis of Neutral Lipids

(2013) Kelly V. Ruggles et al.   Annual Review of Nutrition

Arv1 Regulates PM and ER Membrane Structure and Homeostasis But is Dispensable for Intracellular Sterol Transport

(2013) Alexander G. Georgiev et al.   TRAFFIC

Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6

(2011) Christopher D. Green et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Phospholipid homeostasis and lipotoxic cardiomyopathy

(2011) Hui-Ying Lim et al.   FLY

Loss of Subcellular Lipid Transport Due toARV1Deficiency Disrupts Organelle Homeostasis and Activates the Unfolded Protein Response

(2011) Caryn F. Shechtman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets

(2011) Oludotun Adeyo et al.   JOURNAL OF CELL BIOLOGY

Lipotoxicity is glucose-dependent in INS-1E cells but not in human islets and MIN6 cells

(2011) Ernest Sargsyan et al.   Lipids in Health and Disease

ELOVL6 Genetic Variation Is Related to Insulin Sensitivity: A New Candidate Gene in Energy Metabolism

(2011) Sonsoles Morcillo et al.   PLoS One

Decreased Expression ofARV1Results in Cholesterol Retention in the Endoplasmic Reticulum and Abnormal Bile Acid Metabolism

(2010) Fumin Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation

(2010) Suneil K. Koliwad et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of palmitate on ER and cytosolic Ca2+ homeostasis in β-cells

(2009) Kamila S. Gwiazda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Diabetes and apoptosis: lipotoxicity

(2009) Christine M. Kusminski et al.   APOPTOSIS

Conditions of endoplasmic reticulum stress stimulate lipid droplet formation inSaccharomyces cerevisiae

(2009) Weihua Fei et al.   BIOCHEMICAL JOURNAL

Lipid oversupply, selective insulin resistance, and lipotoxicity: Molecular mechanisms

(2009) Jose Antonio Chavez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Fatty liver and lipotoxicity

(2009) Michael Trauner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipid homeostasis, lipotoxicity and the metabolic syndrome

(2009) Roger H. Unger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mitochondrial dysfunction and lipotoxicity

(2009) Patrick Schrauwen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lessons learned from studying families genetically predisposed to type 2 diabetes mellitus

(2009) Kenneth Cusi   Current Diabetes Reports

The Leu262Val polymorphism of presenilin associated rhomboid like protein (PARL) is associated with earlier onset of type 2 diabetes and increased urinary microalbumin creatinine ratio in an Irish case–control population

(2009) M. Hatunic et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids

(2009) Claudio J. Villanueva et al.   HEPATOLOGY

Sterol and Diacylglycerol Acyltransferase Deficiency Triggers Fatty Acid-mediated Cell Death

(2009) Jeanne Garbarino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Good Fat, Essential Cellular Requirements for Triacylglycerol Synthesis to Maintain Membrane Homeostasis in Yeast

(2009) Julia Petschnigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid-Induced ER Stress: Synergistic Effects of Sterols and Saturated Fatty Acids

(2009) Ludovic Pineau et al.   TRAFFIC

Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

(2008) J. M. Haus et al.   DIABETES

The Gregarious Lipid Droplet

(2008) Joel M. Goodman   JOURNAL OF BIOLOGICAL CHEMISTRY

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

(2008) Weihua Fei et al.   JOURNAL OF CELL BIOLOGY

Is Obesity Our Genetic Legacy?

(2008) Alexandra I. F. Blakemore et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Differential regulation of the endoplasmic reticulum stress response in pancreatic β-cells exposed to long-chain saturated and monounsaturated fatty acids

(2008) Eleftheria Diakogiannaki et al.   JOURNAL OF ENDOCRINOLOGY

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

(2008) Tae-Sik Park et al.   JOURNAL OF LIPID RESEARCH

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

(2008) Yi Guo et al.   NATURE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Effects of TCF7L2 Polymorphisms on Obesity in European Populations

(2008) Stéphane Cauchi et al.   Obesity

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS

COPI Complex Is a Regulator of Lipid Homeostasis

(2008) Mathias Beller et al.   PLOS BIOLOGY

Lipid accumulation in non-adipose tissue and lipotoxicity

(2007) N.A. van Herpen et al.   PHYSIOLOGY & BEHAVIOR