Engineered Soluble Monomeric IgG1 CH3 Domain

Soluble Monomeric IgG1 Fc

(2012) Tianlei Ying et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stabilisation of the Fc Fragment of Human IgG1 by Engineered Intradomain Disulfide Bonds

(2012) Gordana Wozniak-Knopp et al.   PLoS One

Shortened Engineered Human Antibody CH2 Domains

(2011) Rui Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibody-based therapeutics to watch in 2011

(2011) Janice M. Reichert   mAbs

Design, expression and characterization of a soluble single-chain functional human neonatal Fc receptor

(2011) Yang Feng et al.   PROTEIN EXPRESSION AND PURIFICATION

Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR

(2010) Takuo Suzuki et al.   JOURNAL OF IMMUNOLOGY

Engineered CH2 domains (nanoantibodies)

(2010) Dimiter S Dimitrov   mAbs

Enhanced antibody half-life improves in vivo activity

(2010) Jonathan Zalevsky et al.   NATURE BIOTECHNOLOGY

Fc-Based Cytokines

(2009) Jalal A Jazayeri et al.   BIODRUGS

Engineered Human Antibody Constant Domains with Increased Stability

(2009) Rui Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development trends for therapeutic antibody fragments

(2009) Aaron L Nelson et al.   NATURE BIOTECHNOLOGY

Structure of an isolated unglycosylated antibody CH2 domain

(2008) Ponraj Prabakaran et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Single-domain antibodies as building blocks for novel therapeutics

(2008) D SAERENS et al.   CURRENT OPINION IN PHARMACOLOGY

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers

(2008) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA