Systematic Proteomic Analysis Identifies β-Site Amyloid Precursor Protein Cleaving Enzyme 2 and 1 (BACE2 and BACE1) Substrates in Pancreatic β-Cells

The pancreatic beta cell surface proteome

(2012) I. Stützer et al.   DIABETOLOGIA

Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons

(2012) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

The Neural Cell Adhesion Molecules L1 and CHL1 Are Cleaved by BACE1 Proteasein Vivo

(2012) Lujia Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bace2 Is a β Cell-Enriched Protease that Regulates Pancreatic β Cell Function and Mass

(2011) Daria Esterházy et al.   Cell Metabolism

Reduced Serum Vitamin D-Binding Protein Levels Are Associated With Type 1 Diabetes

(2011) D. Blanton et al.   DIABETES

Pancreatic islet and progenitor cell surface markers with cell sorting potential

(2011) J. Hald et al.   DIABETOLOGIA

Neuronal Brain-derived Neurotrophic Factor Is Synthesized in Excess, with Levels Regulated by Sortilin-mediated Trafficking and Lysosomal Degradation

(2011) Sarah Felice Evans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic β-Cells and Human Islets

(2011) Carsten Danzer et al.   JOURNAL OF PROTEOME RESEARCH

Absolute quantification of microbial proteomes at different states by directed mass spectrometry

(2011) A. Schmidt et al.   Molecular Systems Biology

Pancreatic Beta Cells Synthesize Neuropeptide Y and Can Rapidly Release Peptide Co-Transmitters

(2011) Matthew D. Whim   PLoS One

Systematic quantification of peptides/proteins in urine using selected reaction monitoring

(2011) Nathalie Selevsek et al.   PROTEOMICS

BACE2 plays a role in the insulin receptor trafficking in pancreatic β-cells

(2010) Silvia Casas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Neurotensin is a regulator of insulin secretion in pancreatic beta-cells

(2010) Sophie Béraud-Dufour et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Secretome proteomics for discovery of cancer biomarkers

(2010) Manousos Makridakis et al.   Journal of Proteomics

Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of disease-specific biomarkers

(2010) Paul Dowling et al.   PROTEOMICS

The pancreatic β-cell in the islet and organ community

(2009) Daniel Eberhard et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

High-throughput generation of selected reaction-monitoring assays for proteins and proteomes

(2009) Paola Picotti et al.   NATURE METHODS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

(2009) Georgina S. Butler et al.   NATURE REVIEWS DRUG DISCOVERY

Identification of β-Secretase (BACE1) Substrates Using Quantitative Proteomics

(2009) Matthew L. Hemming et al.   PLoS One

Gene Silencing of Phogrin Unveils Its Essential Role in Glucose-Responsive Pancreatic  -Cell Growth

(2008) S. Torii et al.   DIABETES

Voltage-Gated Ion Channels in Human Pancreatic  -Cells: Electrophysiological Characterization and Role in Insulin Secretion

(2008) M. Braun et al.   DIABETES

Proteomic analysis of conditioned media from glucose responsive and glucose non-responsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction

(2008) Paul Dowling et al.   ELECTROPHORESIS

Analysis of Cell Surface Proteome Changes via Label-free, Quantitative Mass Spectrometry

(2008) Ralph Schiess et al.   MOLECULAR & CELLULAR PROTEOMICS