Evidence of Ternary Complex Formation inTrypanosoma cruzi trans-Sialidase Catalysis

Insights into the Activity and Specificity of Trypanosoma cruzi trans-Sialidase from Molecular Dynamics Simulations

(2013) Felicity L. Mitchell et al.   BIOCHEMISTRY

Recent structures, evolution and mechanisms of glycosyltransferases

(2012) Christelle Breton et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Exposing the Flexibility of Human Parainfluenza Virus Hemagglutinin-neuraminidase

(2012) Moritz Winger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

How Conformational Dynamics of DNA Polymerase Select Correct Substrates: Experiments and Simulations

(2012) Serdal Kirmizialtin et al.   STRUCTURE

Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: The carbohydrate binding mechanism involves residual sialidase activity

(2011) Pablo Oppezzo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Molecular dynamics simulations and QM/MM studies of the reactivation by 2-PAM of tabun inhibited human acethylcolinesterase

(2011) Arlan da Silva Gonçalves et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Proton Transfer Facilitated by Ligand Binding. An Energetic Analysis of the Catalytic Mechanism ofTrypanosoma cruziTrans-Sialidase

(2010) Gustavo Pierdominici-Sottile et al.   BIOCHEMISTRY

Tryptophan as a Molecular Shovel in the Glycosyl Transfer Activity of Trypanosoma cruzi Trans-sialidase

(2010) Felicity L. Mitchell et al.   BIOPHYSICAL JOURNAL

A novel prokaryotic l-arginine:glycine amidinotransferase is involved in cylindrospermopsin biosynthesis

(2010) Julia Muenchhoff et al.   FEBS Journal

A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence

(2010) S. T. Carvalho et al.   GLYCOBIOLOGY

Dose–Volume Histogram Analysis of the Safety of Proton Beam Therapy for Unresectable Hepatocellular Carcinoma

(2010) Mitsuhiko Kawashima et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Trypanosoma cruziSubverts Host Cell Sialylation and May Compromise Antigen-specific CD8+T Cell Responses

(2010) Leonardo Freire-de-Lima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction betweenPlasmodium falciparumApical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

(2010) Dave Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Validation of a Rapid Immunochromatographic Assay for Diagnosis of Trypanosoma cruzi Infection among Latin-American Migrants in Geneva, Switzerland

(2010) F. Chappuis et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Lactose Binding to Galectin-1 Modulates Structural Dynamics, Increases Conformational Entropy, and Occurs with Apparent Negative Cooperativity

(2010) Irina V. Nesmelova et al.   JOURNAL OF MOLECULAR BIOLOGY

Chagas disease: pushing through the pipeline

(2010) Julie Clayton   NATURE

Chagas disease 101

(2010) Julie Clayton   NATURE

Modulation of Catalytic Function by Differential Plasticity of the Active Site: Case Study ofTrypanosoma cruzitrans-Sialidase andTrypanosoma rangeliSialidase†

(2009) Özlem Demir et al.   BIOCHEMISTRY

Nuclear Magnetic Resonance Structural Characterization of Substrates Bound to the α-2,6-Sialyltransferase, ST6Gal-I

(2009) Shan Liu et al.   BIOCHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

A New Generation of SpecificTrypanosoma cruzi trans-Sialidase Inhibitors

(2008) Sabrina Buchini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic and Mechanistic Analysis ofTrypanosoma cruziTrans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base Catalysis†

(2008) Iben Damager et al.   BIOCHEMISTRY

Mechanistic insights into glycosidase chemistry

(2008) David J Vocadlo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chemical Structure of Major Glycoconjugates from Parasites

(2008) Lucia Mendonca-Previato et al.   CURRENT ORGANIC CHEMISTRY

The Structure ofClostridium perfringensNanI Sialidase and Its Catalytic Intermediates

(2008) Simon L. Newstead et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

MKTOP: a program for automatic construction of molecular topologies

(2008) André A. S. T. Ribeiro et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Structural Characterization of the 1918 Influenza Virus H1N1 Neuraminidase

(2008) X. Xu et al.   JOURNAL OF VIROLOGY