Transcription Factors Sp1 and Hif2α Mediate Induction of the Copper-transporting ATPase ( Atp7a ) Gene in Intestinal Epithelial Cells during Hypoxia

Investigation of Iron Metabolism in Mice Expressing a Mutant Menke’s Copper Transporting ATPase (Atp7a) Protein with Diminished Activity (Brindled; MoBr/y)

(2013) Sukru Gulec et al.   PLoS One

Copper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cells

(2012) Liwei Xie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Intestinal iron absorption

(2012) Brie K. Fuqua et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2α) in intestinal epithelial cells

(2011) Liwei Xie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Exploration of the copper-related compensatory response in the Belgrade rat model of genetic iron deficiency

(2011) Lingli Jiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake

(2011) P. N. Ranganathan et al.   BLOOD

Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

(2011) Matthew Taylor et al.   GASTROENTEROLOGY

Cross-species comparison of genomewide gene expression profiles reveals induction of hypoxia-inducible factor-responsive genes in iron-deprived intestinal epithelial cells

(2010) Zihua Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Alternative splicing of the Menkes copper Atpase (Atp7a) transcript in the rat intestinal epithelium

(2009) James F. Collins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

(2009) Yatrik M. Shah et al.   Cell Metabolism

Menkes disease

(2009) Zeynep Tümer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia

(2009) Yair Benita et al.   NUCLEIC ACIDS RESEARCH