Induction of COX-2 Enzyme and Down-regulation of COX-1 Expression by Lipopolysaccharide (LPS) Control Prostaglandin E2Production in Astrocytes
Published 2012 View Full Article
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Title
Induction of COX-2 Enzyme and Down-regulation of COX-1 Expression by Lipopolysaccharide (LPS) Control Prostaglandin E2Production in Astrocytes
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 9, Pages 6454-6468
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-01-06
DOI
10.1074/jbc.m111.327874
References
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- Astrocytes are very sensitive to develop innate immune responses to lipid-carried short interfering RNA
- (2008) Roser Gorina et al. GLIA
- Expression of Enzymes Involved in the Prostanoid Metabolism by Cortical Astrocytes after LPS-induced Inflammation
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- Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2
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- Elevated microsomal prostaglandin-E synthase–1 in Alzheimer’s disease
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- Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury
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