The Trithorax Group Protein Ash2l Is Essential for Pluripotency and Maintaining Open Chromatin in Embryonic Stem Cells

Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30

(2012) Yong Chen et al.   CELL RESEARCH

Genomic Approaches to Deconstruct Pluripotency

(2011) Yuin-Han Loh et al.   Annual Review of Genomics and Human Genetics

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Chromatin Connections to Pluripotency and Cellular Reprogramming

(2011) Stuart H. Orkin et al.   CELL

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

(2011) Hao Jiang et al.   CELL

Human telomeric proteins occupy selective interstitial sites

(2011) Dong Yang et al.   CELL RESEARCH

Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding

(2011) Yong Chen et al.   EMBO REPORTS

Discovering pluripotency: 30 years of mouse embryonic stem cells

(2011) Martin Evans   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain

(2011) Sabina Sarvan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

(2011) Matthew D. Young et al.   NUCLEIC ACIDS RESEARCH

Structural and Biochemical Insights into MLL1 Core Complex Assembly

(2011) Vanja Avdic et al.   STRUCTURE

A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

(2010) Jonghwan Kim et al.   CELL

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells

(2010) Keriayn N. Smith et al.   Cell Stem Cell

Chromatin plasticity and genome organization in pluripotent embryonic stem cells

(2010) Anna Mattout et al.   CURRENT OPINION IN CELL BIOLOGY

Parallel gateways to pluripotency: open chromatin in stem cells and development

(2010) Fong Ming Koh et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Ash2l interacts with Tbx1 and is required during early embryogenesis

(2010) Jason Z Stoller et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human

(2010) Shivani Malik et al.   FEBS Journal

Chromatin signature of embryonic pluripotency is established during genome activation

(2010) Nadine L. Vastenhouw et al.   NATURE

Open chromatin in pluripotency and reprogramming

(2010) Alexandre Gaspar-Maia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Global Chromatin Architecture Reflects Pluripotency and Lineage Commitment in the Early Mouse Embryo

(2010) Kashif Ahmed et al.   PLoS One

An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

(2010) Fang Cao et al.   PLoS One

CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

(2010) Michael P. Schnetz et al.   PLoS Genetics

SOAP2: an improved ultrafast tool for short read alignment

(2009) R. Li et al.   BIOINFORMATICS

Understanding the Words of Chromatin Regulation

(2009) Jiang I. Wu et al.   CELL

Histone H3 lysine 4 (H3K4) methylation in development and differentiation

(2009) Joel C. Eissenberg et al.   DEVELOPMENTAL BIOLOGY

Myc-regulated microRNAs attenuate embryonic stem cell differentiation

(2009) Chin-Hsing Lin et al.   EMBO JOURNAL

Transcriptional competence in pluripotency

(2009) E. V.S. Raghu Ram et al.   GENES & DEVELOPMENT

SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state

(2009) S. Bilodeau et al.   GENES & DEVELOPMENT

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

(2009) M. P. Schnetz et al.   GENOME RESEARCH

Mechanisms of transcriptional repression by histone lysine methylation

(2009) Philip Hublitz et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation

(2009) Jana Krejčí et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Systems-level dynamic analyses of fate change in murine embryonic stem cells

(2009) Rong Lu et al.   NATURE

Gene Regulation and Epigenetic Remodeling in Murine Embryonic Stem Cells by c-Myc

(2009) Chin-Hsing Lin et al.   PLoS One

Global Transcription in Pluripotent Embryonic Stem Cells

(2008) Sol Efroni et al.   Cell Stem Cell

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

(2008) Jiancong Liang et al.   NATURE CELL BIOLOGY

Transcription factor Ap2  associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription

(2008) C. C. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb Repressive Complex 2 Is Dispensable for Maintenance of Embryonic Stem Cell Pluripotency

(2008) Stormy J. Chamberlain et al.   STEM CELLS

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY