A Novel Role of Krüppel-like Factor 8 in DNA Repair in Breast Cancer Cells

The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

(2012) Mathew Sajish et al.   Nature Chemical Biology

Krüppel-Like Factor 8 (KLF8) Is Expressed in Gliomas of Different WHO Grades and Is Essential for Tumor Cell Proliferation

(2012) Oliver Schnell et al.   PLoS One

Role of autophagy in chemoresistance: Regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA–PKcs and PARP-1

(2011) Jung-Hoon Yoon et al.   BIOCHEMICAL PHARMACOLOGY

Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

(2011) J. Chad Brenner et al.   CANCER CELL

Identification of Poly (ADP-ribose) Polymerase-1 (PARP-1) as a Novel Krüppel-like Factor 8-interacting and -regulating Protein

(2011) Heng Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic polymorphisms in APE1 are associated with renal cell carcinoma risk in a Chinese population

(2011) Qiang Cao et al.   MOLECULAR CARCINOGENESIS

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

(2011) Siwanon Jirawatnotai et al.   NATURE

Lentivirus-delivered Krüppel-like factor 8 small interfering RNA inhibits gastric cancer cell growth in vitro and in vivo

(2011) Lili Liu et al.   TUMOR BIOLOGY

KLF8 recruits the p300 and PCAF co-activators to its amino terminal activation domain to activate transcription

(2010) Alison M. Urvalek et al.   CELL CYCLE

Up-regulation of Krüppel-Like Factor 8 Promotes Tumor Invasion and Indicates Poor Prognosis for Hepatocellular Carcinoma

(2010) Jia–Chu Li et al.   GASTROENTEROLOGY

Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo

(2010) Wei-Jin Fu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Poly(ADP-Ribose) Polymerase-1 Is a Determining Factor in Crm1-Mediated Nuclear Export and Retention of p65 NF- B upon TLR4 Stimulation

(2010) M. Zerfaoui et al.   JOURNAL OF IMMUNOLOGY

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9

(2010) X Wang et al.   ONCOGENE

Signal transduction by focal adhesion kinase in cancer

(2009) Jihe Zhao et al.   CANCER AND METASTASIS REVIEWS

A unique sequence in the N-terminal regulatory region controls the nuclear localization of KLF8 by cooperating with the C-terminal zinc-fingers

(2009) Tina S Mehta et al.   CELL RESEARCH

Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity

(2009) James E. Cleaver et al.   NATURE REVIEWS GENETICS

Activation of KLF8 Transcription by Focal Adhesion Kinase in Human Ovarian Epithelial and Cancer Cells

(2008) Xianhui Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY