Cdc6 Protein Obstructs Apoptosome Assembly and Consequent Cell Death by Forming Stable Complexes with Activated Apaf-1 Molecules

Cdc6 Protein Activates p27KIP1-bound Cdk2 Protein Only after the Bound p27 Protein Undergoes C-terminal Phosphorylation

(2012) Baasanjav Uranbileg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho-associated Kinase Connects a Cell Cycle-controlling Anchorage Signal to the Mammalian Target of Rapamycin Pathway

(2011) Jung-ha Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian target of rapamycin complex 1 signaling opposes the effects of anchorage loss, leading to activation of Cdk4 and Cdc6 stabilization

(2010) Shiho Arakawa-Takeuchi et al.   FEBS LETTERS

Ras Homolog Enriched in Brain (Rheb) Enhances Apoptotic Signaling

(2010) Sascha Karassek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

The Apaf-1•procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer

(2009) Srinivas Malladi et al.   EMBO JOURNAL

Anoikis: A necessary death program for anchorage-dependent cells

(2008) Paola Chiarugi et al.   BIOCHEMICAL PHARMACOLOGY

Cdc6 Determines Utilization of p21WAF1/CIP1-dependent Damage Checkpoint in S Phase Cells

(2008) Qiuming Kan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6

(2008) Q. Kan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY