Introduction of a Fluorine Atom at C3 of 3-Deazauridine Shifts Its Antimetabolic Activity from Inhibition of CTP Synthetase to Inhibition of Orotidylate Decarboxylase, an Early Event in thede NovoPyrimidine Nucleotide Biosynthesis Pathway

Title
Introduction of a Fluorine Atom at C3 of 3-Deazauridine Shifts Its Antimetabolic Activity from Inhibition of CTP Synthetase to Inhibition of Orotidylate Decarboxylase, an Early Event in thede NovoPyrimidine Nucleotide Biosynthesis Pathway
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 36, Pages 30444-30454
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-06-25
DOI
10.1074/jbc.m112.378091

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