Systems Analysis of Cancer Cell Heterogeneity in Caspase-dependent Apoptosis Subsequent to Mitochondrial Outer Membrane Permeabilization

Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer

(2012) S Hector et al.   BRITISH JOURNAL OF CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy

(2011) Suzanne Hector et al.   GUT

Predicting pKaValues of Substituted Phenols from Atomic Charges: Comparison of Different Quantum Mechanical Methods and Charge Distribution Schemes

(2011) Radka Svobodová Vařeková et al.   Journal of Chemical Information and Modeling

Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release

(2011) H. J. Huber et al.   Molecular Systems Biology

Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

(2011) T. N. Chonghaile et al.   SCIENCE

Mathematical modelling of the mitochondrial apoptosis pathway

(2010) Heinrich J. Huber et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell death

(2010) Heinrich J Huber et al.   BMC Systems Biology

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systems biology analysis of programmed cell death

(2010) Shani Bialik et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dynamics of outer mitochondrial membrane permeabilization during apoptosis

(2009) M Rehm et al.   CELL DEATH AND DIFFERENTIATION

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Procaspase-3 Activation as an Anti-Cancer Strategy: Structure−Activity Relationship of Procaspase-Activating Compound 1 (PAC-1) and Its Cellular Co-Localization with Caspase-3

(2009) Quinn P. Peterson et al.   JOURNAL OF MEDICINAL CHEMISTRY

PAC-1 Activates Procaspase-3 in Vitro through Relief of Zinc-Mediated Inhibition

(2009) Quinn P. Peterson et al.   JOURNAL OF MOLECULAR BIOLOGY

Expression of X-linked inhibitor of apoptosis protein in human colorectal cancer and its correlation with prognosis

(2009) Xiang Guoan et al.   JOURNAL OF SURGICAL ONCOLOGY

Practical Considerations When Using Temperature to Obtain Rate Constants and Activation Thermodynamics of Enzymes with Two Catalytic Steps: Native and N460T-β-Galactosidase (E. coli) as Examples

(2009) John C. Kappelhoff et al.   PROTEIN JOURNAL

Small-Molecule Activators of a Proenzyme

(2009) D. W. Wolan et al.   SCIENCE

Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein

(2008) Carla L. O'Connor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

(2008) R. Z. Orlowski et al.   CLINICAL CANCER RESEARCH

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

(2008) John G. Albeck et al.   MOLECULAR CELL

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY