Modulation of Starch Digestion for Slow Glucose Release through “Toggling” of Activities of Mucosal α-Glucosidases

Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potent α-glucosidase inhibitors

(2011) Weijia Xie et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase

(2011) Kyra Jones et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The effect of heteroatom substitution of sulfur for selenium in glucosidase inhibitors on intestinal α-glucosidase activities

(2011) Razieh Eskandari et al.   CHEMICAL COMMUNICATIONS

Probing the Intestinal α-Glucosidase Enzyme Specificities of Starch-Digesting Maltase-Glucoamylase and Sucrase-Isomaltase: Synthesis and Inhibitory Properties of 3′- and 5′-Maltose-Extended De-O-sulfonated Ponkoranol

(2011) Razieh Eskandari et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structural insight into substrate specificity of human intestinal maltase-glucoamylase

(2011) Limei Ren et al.   Protein & Cell

Synthesis of a biologically active isomer of kotalanol, a naturally occurring glucosidase inhibitor

(2010) Razieh Eskandari et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural Basis for Substrate Selectivity in Human Maltase-Glucoamylase and Sucrase-Isomaltase N-terminal Domains

(2010) Lyann Sim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Towards the elusive structure of kotalanol, a naturally occurring glucosidase inhibitor

(2010) Sankar Mohan et al.   NATURAL PRODUCT REPORTS

Synthesis and biological activity of naturally occurring α-glucosidase inhibitors

(2010) Duncan J. Wardrop et al.   NATURAL PRODUCT REPORTS

Potent Glucosidase Inhibitors: De-O-sulfonated Ponkoranol and Its Stereoisomer

(2010) Razieh Eskandari et al.   ORGANIC LETTERS

New Glucosidase Inhibitors from an Ayurvedic Herbal Treatment for Type 2 Diabetes: Structures and Inhibition of Human Intestinal Maltase-Glucoamylase with Compounds fromSalacia reticulata

(2009) Lyann Sim et al.   BIOCHEMISTRY

Facile synthesis of de-O-sulfated salacinols: Revision of the structure of neosalacinol, a potent α-glucosidase inhibitor

(2009) Genzoh Tanabe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Sulfonium-ion glycosidase inhibitors isolated from Salacia species used in traditional medicine, and related compounds

(2009) Sankar Mohan et al.   COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS

Slowly Digestible Starch: Concept, Mechanism, and Proposed Extended Glycemic Index

(2009) Genyi Zhang et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Salaprionol and Ponkoranol with Thiosugar Sulfonium Sulfate Structure from Salacia prinoides and a-Glucosidase Inhibitory Activity of Ponkoranol and Kotalanol Desulfate

(2009) Masayuki Yoshikawa et al.   HETEROCYCLES

Structure Proof and Synthesis of Kotalanol and De-O-sulfonated Kotalanol, Glycosidase Inhibitors Isolated from an Herbal Remedy for the Treatment of Type-2 Diabetes

(2009) Kumarasamy Jayakanthan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

(2009) R. Z. Cer et al.   NUCLEIC ACIDS RESEARCH

Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases

(2008) Yasuhiro Minami et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hypoglycemic Effect of 13-Membered Ring Thiocyclitol, a Novel α-Glucosidase Inhibitor from Kothala-himbutu (Salacia reticulata)

(2008) Hiromi OE et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Amylolytically-resistant tapioca starch modified by combined treatment of branching enzyme and maltogenic amylase

(2008) Quang-Tri Le et al.   CARBOHYDRATE POLYMERS

α-Glucosidase Inhibitor from Kothala-himbutu (Salacia reticulataWIGHT)

(2008) Sei Ozaki et al.   JOURNAL OF NATURAL PRODUCTS

On the structure of the bioactive constituent from ayurvedic medicine Salacia reticulata: revision of the literature

(2008) Osamu Muraoka et al.   TETRAHEDRON LETTERS

Enzymatic Synthesis and Properties of Highly Branched Rice Starch Amylose and Amylopectin Cluster

(2007) Chang-Kyu Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Human Intestinal Maltase–Glucoamylase: Crystal Structure of the N-Terminal Catalytic Subunit and Basis of Inhibition and Substrate Specificity

(2007) Lyann Sim et al.   JOURNAL OF MOLECULAR BIOLOGY