Design of Bioactive Peptides from Naturally Occurring μ-Conotoxin Structures
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Title
Design of Bioactive Peptides from Naturally Occurring μ-Conotoxin Structures
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 37, Pages 31382-31392
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-07-07
DOI
10.1074/jbc.m112.375733
References
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Note: Only part of the references are listed.- Structurally Diverse μ-Conotoxin PIIIA Isomers Block Sodium Channel NaV1.4
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- A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors
- (2012) Philippe Favreau et al. BRITISH JOURNAL OF PHARMACOLOGY
- Sodium Channel Blockers as Therapeutic Target for Treating Epilepsy: Recent Updates
- (2012) Valentina Zuliani et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Importance of position 8 in μ-conotoxin KIIIA for voltage-gated sodium channel selectivity
- (2011) Annelies Van Der Haegen et al. FEBS Journal
- Lactam-Stabilized Helical Analogues of the Analgesic μ-Conotoxin KIIIA
- (2011) Keith K. Khoo et al. JOURNAL OF MEDICINAL CHEMISTRY
- Interactions of Key Charged Residues Contributing to Selective Block of Neuronal Sodium Channels by -Conotoxin KIIIA
- (2011) J. R. McArthur et al. MOLECULAR PHARMACOLOGY
- Orientation of -Conotoxin PIIIA in a Sodium Channel Vestibule, Based on Voltage Dependence of Its Binding
- (2011) J. R. McArthur et al. MOLECULAR PHARMACOLOGY
- Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels
- (2011) Enrico Leipold et al. NEUROPHARMACOLOGY
- Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels
- (2011) Marijke Stevens et al. Frontiers in Pharmacology
- Multiple, Distributed Interactions of μ-Conotoxin PIIIA Associated with Broad Targeting among Voltage-Gated Sodium Channels
- (2010) Jeff R. McArthur et al. BIOCHEMISTRY
- Sodium channel SCN1A and epilepsy: Mutations and mechanisms
- (2010) Andrew Escayg et al. EPILEPSIA
- Genetics and cardiac channelopathies
- (2010) Oscar Campuzano et al. GENETICS IN MEDICINE
- Cooccupancy of the Outer Vestibule of Voltage-Gated Sodium Channels by μ-Conotoxin KIIIA and Saxitoxin or Tetrodotoxin
- (2010) Min-Min Zhang et al. JOURNAL OF NEUROPHYSIOLOGY
- Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders
- (2010) Massimo Mantegazza et al. LANCET NEUROLOGY
- The Tetrodotoxin Receptor of Voltage-Gated Sodium Channels—Perspectives from Interactions with μ-Conotoxins
- (2010) Robert J. French et al. Marine Drugs
- Sodium channelopathies of skeletal muscle result from gain or loss of function
- (2010) Karin Jurkat-Rott et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Cyclization of conotoxins to improve their biopharmaceutical properties
- (2010) Richard J. Clark et al. TOXICON
- Structure of the Analgesic μ-Conotoxin KIIIA and Effects on the Structure and Function of Disulfide Deletion†‡
- (2009) Keith K. Khoo et al. BIOCHEMISTRY
- The Role of Thiols and Disulfides on Protein Stability
- (2009) Maulik Trivedi et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Structurally Minimized μ-Conotoxin Analogues as Sodium Channel Blockers: Implications for Designing Conopeptide-Based Therapeutics
- (2008) Tiffany S. Han et al. ChemMedChem
- Neuronally Selective μ-Conotoxins fromConus striatusUtilize an α-Helical Motif to Target Mammalian Sodium Channels
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- NMR-Based Mapping of Disulfide Bridges in Cysteine-Rich Peptides: Application to the μ-Conotoxin SxIIIA
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- Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus
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- Conotoxin modulation of voltage-gated sodium channels
- (2007) J. Ekberg et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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