Protease Activity of Procaspase-8 Is Essential for Cell Survival by Inhibiting Both Apoptotic and Nonapoptotic Cell Death Dependent on Receptor-interacting Protein Kinase 1 (RIP1) and RIP3

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

(2011) William J. Kaiser et al.   NATURE

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

(2011) Andrew Oberst et al.   NATURE

Functional complementation between FADD and RIP1 in embryos and lymphocytes

(2011) Haibing Zhang et al.   NATURE

Enzymatically active single chain caspase-8 maintains T-cell survival during clonal expansion

(2010) S Leverrier et al.   CELL DEATH AND DIFFERENTIATION

Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway

(2009) S Inoue et al.   CELL DEATH AND DIFFERENTIATION

Interaction of FLASH with Arsenite Resistance Protein 2 Is Involved in Cell Cycle Progression at S Phase

(2009) M. Kiriyama et al.   MOLECULAR AND CELLULAR BIOLOGY

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Structural and Biochemical Studies on Procaspase-8: New Insights on Initiator Caspase Activation

(2009) Nadine Keller et al.   STRUCTURE

Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

(2008) Junichi Hitomi et al.   CELL

Novel cell death by downregulation of eEF1A1 expression in tetraploids

(2008) Y Kobayashi et al.   CELL DEATH AND DIFFERENTIATION

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Antigen-mediated T cell expansion regulated by parallel pathways of death

(2008) I. L. Ch'en et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

(2008) B. D. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA