Melittin Modulates Keratinocyte Function through P2 Receptor-dependent ADAM Activation

Bee venom in cancer therapy

(2011) Nada Oršolić   CANCER AND METASTASIS REVIEWS

Online monitoring of metabolism and morphology of peptide-treated neuroblastoma cancer cells and keratinocytes

(2011) Sabine Drechsler et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Unsaturated Fatty Acids Drive Disintegrin and Metalloproteinase (ADAM)-dependent Cell Adhesion, Proliferation, and Migration by Modulating Membrane Fluidity

(2011) Karina Reiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antimicrobial Peptides and Peptaibols, Substitutes for Conventional Antibiotics

(2010) Herve Duclohier   CURRENT PHARMACEUTICAL DESIGN

The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?

(2010) Paul Saftig et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins

(2010) Dove J. Keith et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

P2Y2Nucleotide Receptors Mediate Metalloprotease-dependent Phosphorylation of Epidermal Growth Factor Receptor and ErbB3 in Human Salivary Gland Cells

(2010) Ann M. Ratchford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site

(2010) S. M. Le Gall et al.   JOURNAL OF CELL SCIENCE

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth

(2009) Neelesh R. Soman et al.   JOURNAL OF CLINICAL INVESTIGATION

Bee venom suppresses PMA-mediated MMP-9 gene activation via JNK/p38 and NF-κB-dependent mechanisms

(2009) Hyun-Ji Cho et al.   JOURNAL OF ETHNOPHARMACOLOGY

ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

(2009) Sylvain M. Le Gall et al.   MOLECULAR BIOLOGY OF THE CELL

P2X7 receptor and macrophage function

(2009) Mark D. Wewers et al.   Purinergic Signalling

ADAM10 Regulates Endothelial Permeability and T-Cell Transmigration by Proteolysis of Vascular Endothelial Cadherin

(2008) Beate Schulz et al.   CIRCULATION RESEARCH

Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway

(2008) Shujing Liu et al.   HEPATOLOGY

The Human Cathelicidin LL-37 Modulates the Activities of the P2X7Receptor in a Structure-dependent Manner

(2008) Linda Tomasinsig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADAM10-Mediated E-Cadherin Release Is Regulated by Proinflammatory Cytokines and Modulates Keratinocyte Cohesion in Eczematous Dermatitis

(2008) Thorsten Maretzky et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Effects of Melittin on the Production of Matrix Metalloproteinase-1 and -3 in Rheumatoid Arthritic Fibroblast-Like Synoviocytes

(2008) Seong-Su Nah et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions

(2008) Karina Reiss et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol

(2007) Sam Maher et al.   BIOCHEMICAL PHARMACOLOGY