Structural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) Protein

UHRF1 Promotes Cell Growth and Metastasis Through Repression of p16ink4a in Colorectal Cancer

(2012) Feng Wang et al.   ANNALS OF SURGICAL ONCOLOGY

The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression

(2012) F Babbio et al.   ONCOGENE

M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability

(2012) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1

(2012) K. Arita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition Effect of siRNA-Downregulated UHRF1 on Breast Cancer Growth

(2011) Feng Yan et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2

(2011) Lulu Hu et al.   CELL RESEARCH

S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance

(2011) Jiqin Zhang et al.   CELL RESEARCH

Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein

(2011) Nataliya Nady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties

(2011) Mahmoud Alhosin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis

(2011) Jaime Chu et al.   MOLECULAR BIOLOGY OF THE CELL

PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression

(2011) Eerappa Rajakumara et al.   MOLECULAR CELL

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

(2011) Max Felle et al.   NUCLEIC ACIDS RESEARCH

Control of DNMT1 Abundance in Epigenetic Inheritance by Acetylation, Ubiquitylation, and the Histone Code

(2011) C. Bronner   Science Signaling

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

(2010) Nima Mosammaparast et al.   Annual Review of Biochemistry

UHRF1 is a novel diagnostic marker of lung cancer

(2010) M Unoki et al.   BRITISH JOURNAL OF CANCER

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications

(2010) Hideharu Hashimoto et al.   Epigenetics

Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1

(2010) Weihua Qin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

DNMT1 Stability Is Regulated by Proteins Coordinating Deubiquitination and Acetylation-Driven Ubiquitination

(2010) Z. Du et al.   Science Signaling

UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity

(2009) Mayada Achour et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer

(2009) Wei Jin et al.   BREAST CANCER RESEARCH AND TREATMENT

The multi-domain protein Np95 connects DNA methylation and histone modification

(2009) Andrea Rottach et al.   NUCLEIC ACIDS RESEARCH

The PHD Domain of Np95 (mUHRF1) Is Involved in Large-Scale Reorganization of Pericentromeric Heterochromatin

(2008) Roberto Papait et al.   MOLECULAR BIOLOGY OF THE CELL

UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells

(2008) Jong Kyong Kim et al.   NUCLEIC ACIDS RESEARCH