Gemfibrozil and Fenofibrate, Food and Drug Administration-approved Lipid-lowering Drugs, Up-regulate Tripeptidyl-peptidase 1 in Brain Cells via Peroxisome Proliferator-activated Receptor α

Suppression of Nuclear Factor-κB Activation and Inflammation in Microglia by Physically Modified Saline

(2012) Saurabh Khasnavis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gemfibrozil, a Lipid-lowering Drug, Induces Suppressor of Cytokine Signaling 3 in Glial Cells

(2012) Arunava Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gemfibrozil, a Lipid-Lowering Drug, Upregulates IL-1 Receptor Antagonist in Mouse Cortical Neurons: Implications for Neuronal Self-Defense

(2012) G. T. Corbett et al.   JOURNAL OF IMMUNOLOGY

Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Neuroprotective Parkinson Disease Protein DJ-1 in Astrocytes and Neurons

(2011) Saurabh Khasnavis et al.   Journal of Neuroimmune Pharmacology

Intrathecal tripeptidyl-peptidase 1 reduces lysosomal storage in a canine model of late infantile neuronal ceroid lipofuscinosis

(2011) Brian R. Vuillemenot et al.   MOLECULAR GENETICS AND METABOLISM

Large-volume Intrathecal Enzyme Delivery Increases Survival of a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

(2011) Su Xu et al.   MOLECULAR THERAPY

Functional consequences and rescue potential of pathogenic missense mutations in tripeptidyl peptidase I

(2010) Mariusz Walus et al.   HUMAN MUTATION

Lessons learnt from animal models: pathophysiology of neuropathic lysosomal storage disorders

(2010) Kim M. Hemsley et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Pathophysiology of neuropathic lysosomal storage disorders

(2010) Cinzia Maria Bellettato et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Fibrillar Amyloid- -Activated Human Astroglia Kill Primary Human Neurons via Neutral Sphingomyelinase: Implications for Alzheimer's Disease

(2010) A. Jana et al.   JOURNAL OF NEUROSCIENCE

Gemfibrozil, stretching arms beyond lipid lowering

(2009) Avik Roy et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Treatment of Late Infantile Neuronal Ceroid Lipofuscinosis by CNS Administration of a Serotype 2 Adeno-Associated Virus Expressing CLN2 cDNA

(2008) Stefan Worgall et al.   HUMAN GENE THERAPY

Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis

(2008) David E. Sleat et al.   MOLECULAR GENETICS AND METABOLISM

Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

(2008) Michael Chang et al.   MOLECULAR THERAPY