Transcription Factor-mediated Epigenetic Reprogramming

Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines

(2011) Christoph Bock et al.   CELL

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape

(2011) Bernadett Papp et al.   CELL RESEARCH

Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

(2011) Bryce W. Carey et al.   Cell Stem Cell

Historical Origins of Transdifferentiation and Reprogramming

(2011) Thomas Graf   Cell Stem Cell

Reprogramming Factor Expression Initiates Widespread Targeted Chromatin Remodeling

(2011) Richard P. Koche et al.   Cell Stem Cell

Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

(2011) Rajesh Ambasudhan et al.   Cell Stem Cell

Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons

(2011) Samuele Marro et al.   Cell Stem Cell

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

Chromatin states in pluripotent, differentiated, and reprogrammed cells

(2011) Cynthia L Fisher et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs

(2011) Si Wan Kim et al.   DEVELOPMENTAL BIOLOGY

KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription

(2011) Liangqi Xie et al.   EMBO JOURNAL

Human oocytes reprogram somatic cells to a pluripotent state

(2011) Scott Noggle et al.   NATURE

MicroRNA-mediated conversion of human fibroblasts to neurons

(2011) Andrew S. Yoo et al.   NATURE

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells

(2011) Hao Wu et al.   NATURE

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

(2011) Pengyu Huang et al.   NATURE

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

(2011) Sayaka Sekiya et al.   NATURE

Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells

(2011) Yuki Ohi et al.   NATURE CELL BIOLOGY

Progress in understanding reprogramming to the induced pluripotent state

(2011) Kathrin Plath et al.   NATURE REVIEWS GENETICS

Direct conversion of human fibroblasts to dopaminergic neurons

(2011) U. Pfisterer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

c-Myc Regulates Transcriptional Pause Release

(2010) Peter B. Rahl et al.   CELL

Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming

(2010) Nishant Singhal et al.   CELL

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone

(2010) Jiekai Chen et al.   CELL RESEARCH

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

(2010) Debbie L.C. van den Berg et al.   Cell Stem Cell

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

(2010) Matthew G. Guenther et al.   Cell Stem Cell

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

(2010) Ronghui Li et al.   Cell Stem Cell

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

Nanog Overcomes Reprogramming Barriers and Induces Pluripotency in Minimal Conditions

(2010) Thorold W. Theunissen et al.   CURRENT BIOLOGY

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

(2010) M. Dejosez et al.   GENES & DEVELOPMENT

Jarid2 and PRC2, partners in regulating gene expression

(2010) G. Li et al.   GENES & DEVELOPMENT

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Reprogramming with defined factors: from induced pluripotency to induced transdifferentiation

(2010) M. Masip et al.   MOLECULAR HUMAN REPRODUCTION

Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

(2010) Matthias Stadtfeld et al.   NATURE

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

(2010) Na-Yu Chia et al.   NATURE

Epigenetic memory in induced pluripotent stem cells

(2010) K. Kim et al.   NATURE

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Dynamic single-cell imaging of direct reprogramming reveals an early specifying event

(2010) Zachary D Smith et al.   NATURE BIOTECHNOLOGY

Epigenetic modifications in pluripotent and differentiated cells

(2010) Alexander Meissner   NATURE BIOTECHNOLOGY

Role of the Murine Reprogramming Factors in the Induction of Pluripotency

(2009) Rupa Sridharan et al.   CELL

iPS Cells Can Support Full-Term Development of Tetraploid Blastocyst-Complemented Embryos

(2009) Lan Kang et al.   Cell Stem Cell

Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures

(2009) Mark H. Chin et al.   Cell Stem Cell

Neurogenin3 Is Sufficient for Transdetermination of Hepatic Progenitor Cells into Neo-Islets In Vivo but Not Transdifferentiation of Hepatocytes

(2009) Vijay Yechoor et al.   DEVELOPMENTAL CELL

A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal

(2009) G. Hu et al.   GENES & DEVELOPMENT

PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis

(2009) Pallavi Gupta et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Adult mice generated from induced pluripotent stem cells

(2009) Michael J. Boland et al.   NATURE

iPS cells produce viable mice through tetraploid complementation

(2009) Xiao-yang Zhao et al.   NATURE

Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors

(2009) Jun K. Takeuchi et al.   NATURE

An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network

(2009) L. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming

(2008) Rudolf Jaenisch et al.   CELL

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

(2008) Jonghwan Kim et al.   CELL

Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cells

(2008) Xiaosong Liu et al.   CELL RESEARCH

Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse

(2008) Matthias Stadtfeld et al.   Cell Stem Cell

Global Transcription in Pluripotent Embryonic Stem Cells

(2008) Sol Efroni et al.   Cell Stem Cell

Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells

(2008) Tobias Brambrink et al.   Cell Stem Cell

Hair cell regeneration

(2008) Albert SB Edge et al.   CURRENT OPINION IN NEUROBIOLOGY

Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia

(2008) Anna Kirjavainen et al.   DEVELOPMENTAL BIOLOGY

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

(2008) M. F. Cole et al.   GENES & DEVELOPMENT

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Dissecting direct reprogramming through integrative genomic analysis

(2008) Tarjei S. Mikkelsen et al.   NATURE

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells

(2008) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PU.1 and C/EBP /  convert fibroblasts into macrophage-like cells

(2008) R. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SWI/SNF-Brg1 Regulates Self-Renewal and Occupies Core Pluripotency-Related Genes in Embryonic Stem Cells

(2008) Benjamin L. Kidder et al.   STEM CELLS

Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2

(2008) Carlos F. Pereira et al.   PLoS Genetics

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics