Constant Domain-regulated Antibody Catalysis

Hydrolysis of Coagulation Factors by Circulating IgG Is Associated with a Reduced Risk for Chronic Allograft Nephropathy in Renal Transplanted Patients

(2014) B. Wootla et al.   JOURNAL OF IMMUNOLOGY

Increased serum baseline tryptase levels and extensive skin involvement are predictors for the severity of mast cell activation episodes in children with mastocytosis

(2012) I. Alvarez-Twose et al.   ALLERGY

Constitutive Production of Catalytic Antibodies to a Staphylococcus aureus Virulence Factor and Effect of Infection

(2012) Eric L. Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-integrase abzymes from the sera of HIV-infected patients specifically hydrolyze integrase but nonspecifically cleave short oligopeptides

(2012) Elena S. Odintsova et al.   JOURNAL OF MOLECULAR RECOGNITION

A novel molecular analysis of genes encoding catalytic antibodies

(2012) Damien Le Minoux et al.   MOLECULAR IMMUNOLOGY

Highly efficient method of preparing human catalytic antibody light chains and their biological characteristics

(2011) Emi Hifumi et al.   FASEB JOURNAL

Autoantibodies with enzymatic properties in human autoimmune diseases

(2011) Bharath Wootla et al.   JOURNAL OF AUTOIMMUNITY

Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics

(2011) I. Smirnov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal peptidase I: Cleaving the way to mature proteins

(2011) Sarah M. Auclair et al.   PROTEIN SCIENCE

Proteolytic antibodies activate factor IX in patients with acquired hemophilia

(2010) B. Wootla et al.   BLOOD

Proteolysis activity of IgM antibodies from rheumatoid arthritis patients' sera: evidence of atypical catalytic site

(2010) A. S. Kamalanathan et al.   JOURNAL OF MOLECULAR RECOGNITION

Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure☆

(2010) Alena Janda et al.   MOLECULAR IMMUNOLOGY

A Human Germ Line Antibody Light Chain with Hydrolytic Properties Associated with Multimerization Status

(2009) Vikram Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antigen-specific Proteolysis by Hybrid Antibodies Containing Promiscuous Proteolytic Light Chains Paired with an Antigen-binding Heavy Chain

(2009) Gopal Sapparapu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of anti-prothrombin antibodies in the anti-phospholipid syndrome that display the prothrombinase activity

(2009) Yao-Hsu Yang et al.   RHEUMATOLOGY

Exceptional Amyloid β Peptide Hydrolyzing Activity of Nonphysiological Immunoglobulin Variable Domain Scaffolds

(2008) Hiroaki Taguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The immunoglobulin constant region contributes to affinity and specificity

(2008) Marcela Torres et al.   TRENDS IN IMMUNOLOGY