Allosteric Modulation of Ca2+flux in Ligand-gated Cation Channel (P2X4) by Actions on Lateral Portals

Can selectivity be functionally modulated in ion channels?: Figure 1.

(2011) Riccardo Fesce et al.   JOURNAL OF GENERAL PHYSIOLOGY

Ion access pathway to the transmembrane pore in P2X receptor channels

(2011) Toshimitsu Kawate et al.   JOURNAL OF GENERAL PHYSIOLOGY

Highly conserved tyrosine 37 stabilizes desensitized states and restricts calcium permeability of ATP-gated P2X3 receptor

(2011) Marie Jindrichova et al.   JOURNAL OF NEUROCHEMISTRY

Activation and Regulation of Purinergic P2X Receptor Channels

(2011) C. Coddou et al.   PHARMACOLOGICAL REVIEWS

Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors)

(2011) D. S. K. Samways et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Agonist-Induced Changes in Ca2+ Permeation through the Nociceptor Cation Channel TRPA1

(2010) Yuji Karashima et al.   BIOPHYSICAL JOURNAL

Gated Access to the Pore of a P2X Receptor

(2010) Sebastian Kracun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin

(2010) Estelle Toulme et al.   JOURNAL OF GENERAL PHYSIOLOGY

P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance

(2010) Liam E Browne et al.   NATURE NEUROSCIENCE

Functional relevance of aromatic residues in the first transmembrane domain of P2X receptors

(2009) Marie Jindrichova et al.   JOURNAL OF NEUROCHEMISTRY

Functional and structural identification of amino acid residues of the P2X2receptor channel critical for the voltage- and [ATP]-dependent gating

(2009) Batu Keceli et al.   JOURNAL OF PHYSIOLOGY-LONDON

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

Tunable Calcium Current through TRPV1 Receptor Channels

(2008) Damien S. K. Samways et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gating the pore of P2X receptor channels

(2008) Mufeng Li et al.   NATURE NEUROSCIENCE

TRPV1 shows dynamic ionic selectivity during agonist stimulation

(2008) Man-Kyo Chung et al.   NATURE NEUROSCIENCE

ATP-gated P2X cation-channels

(2008) Michael F. Jarvis et al.   NEUROPHARMACOLOGY

Identification of P2X4 receptor transmembrane residues contributing to channel gating and interaction with ivermectin

(2008) Irena Jelínkova et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY