Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains

Computational Design of a PDZ Domain Peptide Inhibitor that Rescues CFTR Activity

(2012) Kyle E. Roberts et al.   PLoS Computational Biology

Rewiring of PDZ Domain-Ligand Interaction Network Contributed to Eukaryotic Evolution

(2012) Jinho Kim et al.   PLoS Genetics

Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor

(2011) Jeanine F. Amacher et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif

(2011) Takahiko Chimura et al.   BMC GENOMICS

Sequence-specific Long Range Networks in PSD-95/Discs Large/ZO-1 (PDZ) Domains Tune Their Binding Selectivity

(2011) Stefano Gianni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactome-wide prediction of short, disordered protein interaction motifs in humans

(2011) Richard J. Edwards et al.   Molecular BioSystems

DomPep—A General Method for Predicting Modular Domain-Mediated Protein-Protein Interactions

(2011) Lei Li et al.   PLoS One

Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death

(2011) Nicolas Babault et al.   STRUCTURE

Evolving specificity from variability for protein interaction domains

(2011) Tomonori Kaneko et al.   TRENDS IN BIOCHEMICAL SCIENCES

Experimental phasing withSHELXC/D/E: combining chain tracing with density modification

(2010) George M. Sheldrick   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Engineering Peptide Inhibitors To Overcome PDZ Binding Promiscuity

(2010) Lars Vouilleme et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Stabilizing Influence: CAL PDZ Inhibition Extends the Half-Life of ΔF508-CFTR

(2010) Patrick R. Cushing et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PDZ domains and their binding partners: structure, specificity, and modification

(2010) Ho-Jin Lee et al.   Cell Communication and Signaling

Structure-Based Prediction of the Peptide Sequence Space Recognized by Natural and Synthetic PDZ Domains

(2010) Colin A. Smith et al.   JOURNAL OF MOLECULAR BIOLOGY

The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell–Matrix Adhesion

(2010) Tyson R. Shepherd et al.   JOURNAL OF MOLECULAR BIOLOGY

A physical model for PDZ-domain/peptide interactions

(2010) Kristian Kaufmann et al.   JOURNAL OF MOLECULAR MODELING

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Halogen bonding: an electrostatically-driven highly directional noncovalent interaction

(2010) Peter Politzer et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Inferring PDZ Domain Multi-Mutant Binding Preferences from Single-Mutant Data

(2010) Elena Zaslavsky et al.   PLoS One

Stereoelectronic and steric effects in side chains preorganize a protein main chain

(2010) M. D. Shoulders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for PDZ domains in bacteria, yeast, and plants

(2010) Christopher P. Ponting   PROTEIN SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled

(2009) Ho-Jin Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery and Characterization of a Small Molecule Inhibitor of the PDZ Domain of Dishevelled

(2009) David Grandy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanism of Inward Rectifier Potassium Channel 2.3 Regulation by Tax-Interacting Protein-1

(2009) Xiaojie Yan et al.   JOURNAL OF MOLECULAR BIOLOGY

Evolutionary Expansion and Specialization of the PDZ Domains

(2009) O. Sakarya et al.   MOLECULAR BIOLOGY AND EVOLUTION

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

(2009) T. S. Thorsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hidden dynamic allostery in a PDZ domain

(2009) C. M. Petit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Graphical models of protein-protein interaction specificity from correlated mutations and interaction data

(2009) John Thomas et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Rapid Evolution of Functional Complexity in a Domain Family

(2009) A. Ernst et al.   Science Signaling

Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias

(2008) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A magic triangle for experimental phasing of macromolecules

(2008) Tobias Beck et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

5-Amino-2,4,6-triiodoisophthalic acid monohydrate

(2008) Tobias Beck et al.   ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE

The Relative Binding Affinities of PDZ Partners for CFTR: A Biochemical Basis for Efficient Endocytic Recycling†

(2008) Patrick R. Cushing et al.   BIOCHEMISTRY

Structural Basis of β-Catenin Recognition by Tax-interacting Protein-1

(2008) Jinxiu Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Predicting PDZ domain–peptide interactions from primary sequences

(2008) Jiunn R Chen et al.   NATURE BIOTECHNOLOGY

A Specificity Map for the PDZ Domain Family

(2008) Raffi Tonikian et al.   PLOS BIOLOGY