The Mammaliande NovoDNA Methyltransferases DNMT3A and DNMT3B Are Also DNA 5-Hydroxymethylcytosine Dehydroxymethylases
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Mammaliande NovoDNA Methyltransferases DNMT3A and DNMT3B Are Also DNA 5-Hydroxymethylcytosine Dehydroxymethylases
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 40, Pages 33116-33121
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-08-17
DOI
10.1074/jbc.c112.406975
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
- (2015) Michael Christoph Haffner et al. Oncotarget
- Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation
- (2012) Yotaro Kudo et al. CANCER SCIENCE
- Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
- (2012) Hideharu Hashimoto et al. NUCLEIC ACIDS RESEARCH
- Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation
- (2012) J. Song et al. SCIENCE
- Active DNA demethylation by Gadd45 and DNA repair
- (2012) Christof Niehrs et al. TRENDS IN CELL BIOLOGY
- 5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations
- (2011) S.-G. Jin et al. CANCER RESEARCH
- Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond
- (2011) Junjie U. Guo et al. CELL CYCLE
- Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
- (2011) H. Wu et al. GENES & DEVELOPMENT
- The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
- (2011) Tian-Peng Gu et al. NATURE
- Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
- (2011) Khursheed Iqbal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos
- (2011) A. Inoue et al. SCIENCE
- Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
- (2011) Y.-F. He et al. SCIENCE
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
- (2011) Mark Wossidlo et al. Nature Communications
- 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
- (2011) Hume Stroud et al. GENOME BIOLOGY
- Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
- (2010) Shinsuke Ito et al. NATURE
- Active DNA demethylation: many roads lead to Rome
- (2010) Susan C. Wu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Active DNA Demethylation Mediated by DNA Glycosylases
- (2009) Jian-Kang Zhu Annual Review of Genetics
- Cytosine-5-methyltransferases add aldehydes to DNA
- (2009) Zita Liutkevičiūtė et al. Nature Chemical Biology
- Heat-Shock and Redox-Dependent Functional Switching of an h-Type Arabidopsis Thioredoxin from a Disulfide Reductase to a Molecular Chaperone
- (2009) S. K. Park et al. PLANT PHYSIOLOGY
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
- (2009) S. Kriaucionis et al. SCIENCE
- The Colorful History of Active DNA Demethylation
- (2008) Steen K.T. Ooi et al. CELL
- H2O2-dependent Hyperoxidation of Peroxiredoxin 6 (Prdx6) Plays a Role in Cellular Toxicity via Up-regulation of iPLA2 Activity
- (2008) So Yong Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclical DNA methylation of a transcriptionally active promoter
- (2008) Raphaël Métivier et al. NATURE
- Mammalian DNA Methyltransferases: A Structural Perspective
- (2008) Xiaodong Cheng et al. STRUCTURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started