Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)

Presenting your structures: theCCP4mgmolecular-graphics software

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Cerebral cavernous malformations: from genes to proteins to disease

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A mechanism of Rap1-induced stabilization of endothelial cell–cell junctions

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Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases

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Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation

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Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction

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What Makes Ras an Efficient Molecular Switch: A Computational, Biophysical, and Structural Study of Ras-GDP Interactions with Mutants of Raf

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The FERM domain: organizing the structure and function of FAK

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The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

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ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

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Rap1 and its effector KRIT1/CCM1 regulate  -catenin signaling

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The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

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The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

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Regulation of cardiovascular development and integrity by the heart of glass–cerebral cavernous malformation protein pathway

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Cell–cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors

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Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II

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The Rap–RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

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Structural and functional differences between KRIT1A and KRIT1B isoforms: A framework for understanding CCM pathogenesis

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A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells

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Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis

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Specificity in Ras and Rap Signaling

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RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences

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krit1 Modulates β1-integrin-mediated Endothelial Cell Proliferation

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