Specialized Hsp70 Chaperone (HscA) Binds Preferentially to the Disordered Form, whereas J-protein (HscB) Binds Preferentially to the Structured Form of the Iron-Sulfur Cluster Scaffold Protein (IscU)

Deconvolution of Two-Dimensional NMR Spectra by Fast Maximum Likelihood Reconstruction: Application to Quantitative Metabolomics

(2011) Roger A. Chylla et al.   ANALYTICAL CHEMISTRY

Native-State Interconversion of a Metamorphic Protein Requires Global Unfolding

(2011) Robert C. Tyler et al.   BIOCHEMISTRY

Three hydrophobic amino acids in Escherichia coli HscB make the greatest contribution to the stability of the HscB-IscU complex

(2011) Anna K Füzéry et al.   BMC BIOCHEMISTRY

Disordered form of the scaffold protein IscU is the substrate for iron-sulfur cluster assembly on cysteine desulfurase

(2011) J. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energetics of Nucleotide-Induced DnaK Conformational States

(2010) Stefka G. Taneva et al.   BIOCHEMISTRY

Tissue-specific splicing of ISCU results in a skeletal muscle phenotype in myopathy with lactic acidosis, while complete loss of ISCU results in early embryonic death in mice

(2010) Angelica Nordin et al.   HUMAN GENETICS

Comprehensive and Cost-Effective NMR Spectroscopy of Methyl Groups in Large Proteins

(2010) Renee Otten et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase

(2010) Sandeep K Sharma et al.   Nature Chemical Biology

Building Fe–S proteins: bacterial strategies

(2010) Béatrice Py et al.   NATURE REVIEWS MICROBIOLOGY

Structure and Dynamics of the Iron−Sulfur Cluster Assembly Scaffold Protein IscU and Its Interaction with the Cochaperone HscB

(2009) Jin Hae Kim et al.   BIOCHEMISTRY

Linking folding and binding

(2009) Peter E Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Disaggregating Chaperones: An Unfolding Story

(2009) Sandeep Sharma et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Splice Mutation in the Iron-Sulfur Cluster Scaffold Protein ISCU Causes Myopathy with Exercise Intolerance

(2008) Fanny Mochel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases

(2008) Roland Lill et al.   Annual Review of Biochemistry

Studies on the Mechanism of Catalysis of Iron−Sulfur Cluster Transfer from IscU[2Fe2S] by HscA/HscB Chaperones†

(2008) Francesco Bonomi et al.   BIOCHEMISTRY

Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect

(2008) A. Olsson et al.   HUMAN MOLECULAR GENETICS

The Asymmetric Trimeric Architecture of [2Fe–2S] IscU: Implications for Its Scaffolding during Iron–Sulfur Cluster Biosynthesis

(2008) Yoshimitsu Shimomura et al.   JOURNAL OF MOLECULAR BIOLOGY

BIOCHEMISTRY: Metamorphic Proteins

(2008) A. G. Murzin   SCIENCE