Crystal Structure of Perakine Reductase, Founding Member of a Novel Aldo-Keto Reductase (AKR) Subfamily That Undergoes Unique Conformational Changes during NADPH Binding

Regiospecific, Enantiospecific Total Synthesis of C-19 Methyl Substituted Sarpagine Alkaloids Dihydroperaksine-17-al and Dihydroperaksine

(2011) Rahul V. Edwankar et al.   ORGANIC LETTERS

The evolution of function in strictosidine synthase-like proteins

(2011) Michael A. Hicks et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis

(2010) Krithika Sundaram et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Facile Chemoenzymatic Approach: One-Step Syntheses of Monoterpenoid Indole Alkaloids

(2010) Hong-Bin Zou et al.   Chemistry-An Asian Journal

Autoindexing with outlier rejection and identification of superimposed lattices

(2010) Nicholas K. Sauter et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase

(2010) Judith Scoble et al.   JOURNAL OF MOLECULAR BIOLOGY

The Three-Dimensional Structure of AKR11B4, a Glycerol Dehydrogenase from Gluconobacter oxydans, Reveals a Tryptophan Residue as an Accelerator of Reaction Turnover

(2010) Nina Richter et al.   JOURNAL OF MOLECULAR BIOLOGY

Integrating carbon–halogen bond formation into medicinal plant metabolism

(2010) Weerawat Runguphan et al.   NATURE

Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids

(2009) Liuqing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aza-Tryptamine Substrates in Monoterpene Indole Alkaloid Biosynthesis

(2009) Hyang-Yeol Lee et al.   CHEMISTRY & BIOLOGY

Characterization of Two Novel Aldo–Keto Reductases from Arabidopsis: Expression Patterns, Broad Substrate Specificity, and an Open Active-Site Structure Suggest a Role in Toxicant Metabolism Following Stress

(2009) Paul J. Simpson et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of Human Liver Δ4-3-Ketosteroid 5β-Reductase (AKR1D1) and Implications for Substrate Binding and Catalysis

(2008) Luigi Di Costanzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia

(2008) Lianli Sun et al.   PLANT MOLECULAR BIOLOGY

3D-Structure and function of strictosidine synthase – the key enzyme of monoterpenoid indole alkaloid biosynthesis

(2008) Joachim Stöckigt et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Barley aldose reductase: Structure, cofactor binding, and substrate recognition in the aldo/keto reductase 4C family

(2008) Johan G. Olsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS