Chemoenzymatic Synthesis of Heparin Oligosaccharides with both Anti-factor Xa and Anti-factor IIa Activities

Synthetic heparin

(2012) Robert J Linhardt et al.   CURRENT OPINION IN PHARMACOLOGY

Uncovering Biphasic Catalytic Mode of C5-epimerase in Heparan Sulfate Biosynthesis

(2012) Juzheng Sheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of 3-O-sulfonated heparan sulfate octasaccharides that inhibit the herpes simplex virus type 1 host–cell interaction

(2011) Yu-Peng Hu et al.   Nature Chemistry

Chemoenzymatic Synthesis of Homogeneous Ultralow Molecular Weight Heparins

(2011) Y. Xu et al.   SCIENCE

Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

(2010) Renpeng Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Successful use of fondaparinux in a patient with a mechanical heart valve replacement and a history of heparin-induced thrombocytopenia

(2010) Tia L. Corbett et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Enzymatic route to preparative-scale synthesis of UDP–GlcNAc/GalNAc, their analogues and GDP–fucose

(2010) Guohui Zhao et al.   Nature Protocols

Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure−Activity Relationship Studies

(2009) Sailaja Arungundram et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of biologically active heparan sulfate and heparin using an enzyme-based approach

(2009) Sherket Peterson et al.   NATURAL PRODUCT REPORTS

Lessons learned from the contamination of heparin

(2009) Haiying Liu et al.   NATURAL PRODUCT REPORTS

Solution Structures of Chemoenzymatically Synthesized Heparin and Its Precursors

(2008) Zhenqing Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SR123781A: A New Once-Daily Synthetic Oligosaccharide Anticoagulant for Thromboprophylaxis After Total Hip Replacement Surgery

(2008) Michael R. Lassen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY