The N-terminal 20-Amino Acid Region of Guanine Nucleotide Exchange Factor Vav1 Plays a Distinguished Role in T Cell Receptor-mediated Calcium Signaling

Vav1 Oncogenic Mutation Inhibits T Cell Receptor-induced Calcium Mobilization through Inhibition of Phospholipase Cγ1 Activation

(2012) Mira Knyazhitsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vav1-Mediated Scaffolding Interactions Stabilize SLP-76 Microclusters and Contribute to Antigen-Dependent T Cell Responses

(2011) N. R. Sylvain et al.   Science Signaling

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

(2010) Bingke Yu et al.   CELL

Guanine nucleotide exchange factors for RhoGTPases: Good therapeutic targets for cancer therapy?

(2010) Galit Lazer et al.   CELLULAR SIGNALLING

VAV2 regulates epidermal growth factor receptor endocytosis and degradation

(2010) S Thalappilly et al.   ONCOGENE

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Rho GTPases in hematopoiesis and hemopathies

(2009) J. C. Mulloy et al.   BLOOD

Vav Links the T Cell Antigen Receptor to the Actin Cytoskeleton and T Cell Activation Independently of Intrinsic Guanine Nucleotide Exchange Activity

(2009) Ana V. Miletic et al.   PLoS One

Function of the Nucleotide Exchange Activity of Vav1 in T Cell Development and Activation

(2009) A. Saveliev et al.   Science Signaling

The Guanine Nucleotide Exchange Factors Trio, Ect2, and Vav3 Mediate the Invasive Behavior of Glioblastoma

(2008) Bodour Salhia et al.   AMERICAN JOURNAL OF PATHOLOGY

Rac GTPases play critical roles in early T-cell development

(2008) C. Dumont et al.   BLOOD